Cargando…
mTORC2/Akt activation in adipocytes is required for adipose tissue inflammation in tuberculosis
BACKGROUND: Mycobacterium tuberculosis has co-evolved with the human host, adapting to exploit the immune system for persistence and transmission. While immunity to tuberculosis (TB) has been intensively studied in the lung and lymphoid system, little is known about the participation of adipose tiss...
Autores principales: | Martinez, Nuria, Cheng, Catherine Y., Ketheesan, Natkunam, Cullen, Aidan, Tang, Yuefeng, Lum, Josephine, West, Kim, Poidinger, Michael, Guertin, David A., Singhal, Amit, Kornfeld, Hardy |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642333/ https://www.ncbi.nlm.nih.gov/pubmed/31279779 http://dx.doi.org/10.1016/j.ebiom.2019.06.052 |
Ejemplares similares
-
Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease
por: Lee, Peter L., et al.
Publicado: (2016) -
Dynamic Adipocyte Phosphoproteome Reveals that Akt Directly Regulates mTORC2
por: Humphrey, Sean J., et al.
Publicado: (2013) -
Regulation of adiposity by mTORC1
por: Magdalon, Juliana, et al.
Publicado: (2017) -
Adipose tissue mTORC2 regulates ChREBP-driven de novo lipogenesis and hepatic glucose metabolism
por: Tang, Yuefeng, et al.
Publicado: (2016) -
mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia
por: Paolella, Lauren M., et al.
Publicado: (2019)