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Paf1C regulates RNA polymerase II progression by modulating elongation rate

Elongation factor Paf1C regulates several stages of the RNA polymerase II (Pol II) transcription cycle, although it is unclear how it modulates Pol II distribution and progression in mammalian cells. We found that conditional ablation of Paf1 resulted in the accumulation of unphosphorylated and Ser5...

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Detalles Bibliográficos
Autores principales:	Hou, Liming, Wang, Yating, Liu, Yu, Zhang, Nan, Shamovsky, Ilya, Nudler, Evgeny, Tian, Bin, Dynlacht, Brian David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2019
Materias:	PNAS Plus
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642404/ https://www.ncbi.nlm.nih.gov/pubmed/31249142 http://dx.doi.org/10.1073/pnas.1904324116

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