Aryl hydrocarbon receptor nuclear translocator-like (ARNTL/BMAL1) is associated with bevacizumab resistance in colorectal cancer via regulation of vascular endothelial growth factor A

BACKGROUND: The identification of new biomarkers and the development of novel, targetable contexts of vulnerability are of urgent clinical need in drug-resistant metastatic colorectal cancer (mCRC). Aryl-Hydrocarbon-Receptor-Nuclear-Translocator-Like (ARNTL/BMAL1) is a circadian clock-regulated tran...

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Detalles Bibliográficos
Autores principales: Burgermeister, Elke, Battaglin, Francesca, Eladly, Fagr, Wu, Wen, Herweck, Frank, Schulte, Nadine, Betge, Johannes, Härtel, Nicolai, Kather, Jakob N., Weis, Cleo-Aron, Gaiser, Timo, Marx, Alexander, Weiss, Christel, Hofheinz, Ralf, Miller, Ian S., Loupakis, Fotios, Lenz, Heinz-Josef, Byrne, Annette T., Ebert, Matthias P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642438/
https://www.ncbi.nlm.nih.gov/pubmed/31300350
http://dx.doi.org/10.1016/j.ebiom.2019.07.004

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