Radiotherapy for recurrent central Giant cell granuloma: a case report

BACKGROUND: Central giant cell granuloma (CGCG) is a rare, non-neoplastic, benign lesion that exhibits expansive and osteolytic biological behavior. CGCG treatment and management is challenging for clinicians. CASE PRESENTATION: This report presents the treatment and management of recurrent, aggress...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, He, Zelai, Wang, Gengming, Jiang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642559/
https://www.ncbi.nlm.nih.gov/pubmed/31324249
http://dx.doi.org/10.1186/s13014-019-1336-7
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author Zhang, Qi
He, Zelai
Wang, Gengming
Jiang, Hao
author_facet Zhang, Qi
He, Zelai
Wang, Gengming
Jiang, Hao
author_sort Zhang, Qi
collection PubMed
description BACKGROUND: Central giant cell granuloma (CGCG) is a rare, non-neoplastic, benign lesion that exhibits expansive and osteolytic biological behavior. CGCG treatment and management is challenging for clinicians. CASE PRESENTATION: This report presents the treatment and management of recurrent, aggressive CGCG after surgical resection. After informed consent was obtained, the patient underwent radiotherapy. The lesion size was reduced significantly, with no evidence of recurrence or malignant transformation. CONCLUSIONS: This treatment experience indicates that radiotherapy can be used as a rescue treatment for complicated CGCG involving vital neurovascular structures of the cranial base.
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spelling pubmed-66425592019-07-29 Radiotherapy for recurrent central Giant cell granuloma: a case report Zhang, Qi He, Zelai Wang, Gengming Jiang, Hao Radiat Oncol Case Report BACKGROUND: Central giant cell granuloma (CGCG) is a rare, non-neoplastic, benign lesion that exhibits expansive and osteolytic biological behavior. CGCG treatment and management is challenging for clinicians. CASE PRESENTATION: This report presents the treatment and management of recurrent, aggressive CGCG after surgical resection. After informed consent was obtained, the patient underwent radiotherapy. The lesion size was reduced significantly, with no evidence of recurrence or malignant transformation. CONCLUSIONS: This treatment experience indicates that radiotherapy can be used as a rescue treatment for complicated CGCG involving vital neurovascular structures of the cranial base. BioMed Central 2019-07-19 /pmc/articles/PMC6642559/ /pubmed/31324249 http://dx.doi.org/10.1186/s13014-019-1336-7 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Zhang, Qi
He, Zelai
Wang, Gengming
Jiang, Hao
Radiotherapy for recurrent central Giant cell granuloma: a case report
title Radiotherapy for recurrent central Giant cell granuloma: a case report
title_full Radiotherapy for recurrent central Giant cell granuloma: a case report
title_fullStr Radiotherapy for recurrent central Giant cell granuloma: a case report
title_full_unstemmed Radiotherapy for recurrent central Giant cell granuloma: a case report
title_short Radiotherapy for recurrent central Giant cell granuloma: a case report
title_sort radiotherapy for recurrent central giant cell granuloma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642559/
https://www.ncbi.nlm.nih.gov/pubmed/31324249
http://dx.doi.org/10.1186/s13014-019-1336-7
work_keys_str_mv AT zhangqi radiotherapyforrecurrentcentralgiantcellgranulomaacasereport
AT hezelai radiotherapyforrecurrentcentralgiantcellgranulomaacasereport
AT wanggengming radiotherapyforrecurrentcentralgiantcellgranulomaacasereport
AT jianghao radiotherapyforrecurrentcentralgiantcellgranulomaacasereport

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