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Absence of an embryonic stem cell DNA methylation signature in human cancer

BACKGROUND: Differentiated cells that arise from stem cells in early development contain DNA methylation features that provide a memory trace of their fetal cell origin (FCO). The FCO signature was developed to estimate the proportion of cells in a mixture of cell types that are of fetal origin and...

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Detalles Bibliográficos
Autores principales:	Zhang, Ze, Wiencke, John K., Koestler, Devin C., Salas, Lucas A., Christensen, Brock C., Kelsey, Karl T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642562/ https://www.ncbi.nlm.nih.gov/pubmed/31324166 http://dx.doi.org/10.1186/s12885-019-5932-6

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