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Efficacy and safety of electric heating moxibustion for perennial allergic rhinitis: protocol for a randomized controlled trial

BACKGROUND: Allergic rhinitis (AR) is an IgE-mediated disease that adversely affects quality of life. Many studies report that moxibustion is an effective treatment for perennial allergic rhinitis (PAR). However, it is difficult to perform moxibustion on the face because of possible burning of the s...

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Autores principales: Jung, Chan-Yung, Cho, Min-Jin, Kang, Ha-Ra, Hong, Seung-Ug, Sung, Won-Suk, Kim, Eun-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642592/
https://www.ncbi.nlm.nih.gov/pubmed/31324214
http://dx.doi.org/10.1186/s13063-019-3550-x
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author Jung, Chan-Yung
Cho, Min-Jin
Kang, Ha-Ra
Hong, Seung-Ug
Sung, Won-Suk
Kim, Eun-Jung
author_facet Jung, Chan-Yung
Cho, Min-Jin
Kang, Ha-Ra
Hong, Seung-Ug
Sung, Won-Suk
Kim, Eun-Jung
author_sort Jung, Chan-Yung
collection PubMed
description BACKGROUND: Allergic rhinitis (AR) is an IgE-mediated disease that adversely affects quality of life. Many studies report that moxibustion is an effective treatment for perennial allergic rhinitis (PAR). However, it is difficult to perform moxibustion on the face because of possible burning of the skin and the noxious effects of smoke. Electric heating moxibustion does not have these limitations. The purpose of this clinical trial is to assess the possibility of treating PAR with electric heating moxibustion and to assess the feasibility of conducting a clinical test on a larger scale. METHODS: This is a randomized, open-label, assessor-blind, parallel-design pilot clinical study. We will recruit 40 eligible participants and randomly allocate them into an electric heating moxibustion group or an acupuncture group at a 1:1 ratio. Patients in both groups will receive eight treatments over 4 weeks, and the final follow-up will be 4 weeks after the last treatment. Eleven acupuncture points will be used for patients in both groups (EX-HN3 and bilateral EX-HN-8, LI20, LI4, GB20, and ST36). The primary outcome measure is change in the Total Nasal Symptom Score, and the secondary outcome measures are changes in the Rhinoconjunctivitis Quality of Life Questionnaire, nasal endoscopy index for pattern identification, pattern identification questionnaire for AR, total IgE, eosinophil count, and adverse effects. DISCUSSION: This clinical trial will examine the effect of electric heating moxibustion on PAR. TRIAL REGISTRATION: ClinicalTrials.gov, NCT03342105. Registered on 14 November 2017. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13063-019-3550-x) contains supplementary material, which is available to authorized users.
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spelling pubmed-66425922019-07-29 Efficacy and safety of electric heating moxibustion for perennial allergic rhinitis: protocol for a randomized controlled trial Jung, Chan-Yung Cho, Min-Jin Kang, Ha-Ra Hong, Seung-Ug Sung, Won-Suk Kim, Eun-Jung Trials Study Protocol BACKGROUND: Allergic rhinitis (AR) is an IgE-mediated disease that adversely affects quality of life. Many studies report that moxibustion is an effective treatment for perennial allergic rhinitis (PAR). However, it is difficult to perform moxibustion on the face because of possible burning of the skin and the noxious effects of smoke. Electric heating moxibustion does not have these limitations. The purpose of this clinical trial is to assess the possibility of treating PAR with electric heating moxibustion and to assess the feasibility of conducting a clinical test on a larger scale. METHODS: This is a randomized, open-label, assessor-blind, parallel-design pilot clinical study. We will recruit 40 eligible participants and randomly allocate them into an electric heating moxibustion group or an acupuncture group at a 1:1 ratio. Patients in both groups will receive eight treatments over 4 weeks, and the final follow-up will be 4 weeks after the last treatment. Eleven acupuncture points will be used for patients in both groups (EX-HN3 and bilateral EX-HN-8, LI20, LI4, GB20, and ST36). The primary outcome measure is change in the Total Nasal Symptom Score, and the secondary outcome measures are changes in the Rhinoconjunctivitis Quality of Life Questionnaire, nasal endoscopy index for pattern identification, pattern identification questionnaire for AR, total IgE, eosinophil count, and adverse effects. DISCUSSION: This clinical trial will examine the effect of electric heating moxibustion on PAR. TRIAL REGISTRATION: ClinicalTrials.gov, NCT03342105. Registered on 14 November 2017. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13063-019-3550-x) contains supplementary material, which is available to authorized users. BioMed Central 2019-07-19 /pmc/articles/PMC6642592/ /pubmed/31324214 http://dx.doi.org/10.1186/s13063-019-3550-x Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Study Protocol
Jung, Chan-Yung
Cho, Min-Jin
Kang, Ha-Ra
Hong, Seung-Ug
Sung, Won-Suk
Kim, Eun-Jung
Efficacy and safety of electric heating moxibustion for perennial allergic rhinitis: protocol for a randomized controlled trial
title Efficacy and safety of electric heating moxibustion for perennial allergic rhinitis: protocol for a randomized controlled trial
title_full Efficacy and safety of electric heating moxibustion for perennial allergic rhinitis: protocol for a randomized controlled trial
title_fullStr Efficacy and safety of electric heating moxibustion for perennial allergic rhinitis: protocol for a randomized controlled trial
title_full_unstemmed Efficacy and safety of electric heating moxibustion for perennial allergic rhinitis: protocol for a randomized controlled trial
title_short Efficacy and safety of electric heating moxibustion for perennial allergic rhinitis: protocol for a randomized controlled trial
title_sort efficacy and safety of electric heating moxibustion for perennial allergic rhinitis: protocol for a randomized controlled trial
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642592/
https://www.ncbi.nlm.nih.gov/pubmed/31324214
http://dx.doi.org/10.1186/s13063-019-3550-x
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