Nanosomal docetaxel lipid suspension based chemotherapy in a pregnant MBC patient – a case report

The current report presents a case of a pregnant woman with breast cancer metastasized to liver and lungs. The standard of care for breast cancer in pregnancy is anthracycline/taxane-based chemotherapy regimens. Docetaxel has shown a favorable toxicity profile during the second and third trimesters...

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Autores principales: Ramaswamy, Rajkumar, Joshi, Nisarg, Khan, Mujtaba A, Siddhara, Seerin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642620/
https://www.ncbi.nlm.nih.gov/pubmed/31406465
http://dx.doi.org/10.2147/OTT.S206573
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author Ramaswamy, Rajkumar
Joshi, Nisarg
Khan, Mujtaba A
Siddhara, Seerin
author_facet Ramaswamy, Rajkumar
Joshi, Nisarg
Khan, Mujtaba A
Siddhara, Seerin
author_sort Ramaswamy, Rajkumar
collection PubMed
description The current report presents a case of a pregnant woman with breast cancer metastasized to liver and lungs. The standard of care for breast cancer in pregnancy is anthracycline/taxane-based chemotherapy regimens. Docetaxel has shown a favorable toxicity profile during the second and third trimesters of pregnancy. A novel nanosomal docetaxel lipid suspension (NDLS) (DoceAqualip), with a proven efficacy and tolerability profile, has been approved in India for the treatment of advanced solid tumors since 2013. We present here a case of a pregnant woman with metastatic breast cancer managed with NDLS based TAC regimen showing a partial response after six cycles. The patient delivered a healthy male child with normal Apgar score and weight at the 32nd week of gestation.
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spelling pubmed-66426202019-08-12 Nanosomal docetaxel lipid suspension based chemotherapy in a pregnant MBC patient – a case report Ramaswamy, Rajkumar Joshi, Nisarg Khan, Mujtaba A Siddhara, Seerin Onco Targets Ther Case Report The current report presents a case of a pregnant woman with breast cancer metastasized to liver and lungs. The standard of care for breast cancer in pregnancy is anthracycline/taxane-based chemotherapy regimens. Docetaxel has shown a favorable toxicity profile during the second and third trimesters of pregnancy. A novel nanosomal docetaxel lipid suspension (NDLS) (DoceAqualip), with a proven efficacy and tolerability profile, has been approved in India for the treatment of advanced solid tumors since 2013. We present here a case of a pregnant woman with metastatic breast cancer managed with NDLS based TAC regimen showing a partial response after six cycles. The patient delivered a healthy male child with normal Apgar score and weight at the 32nd week of gestation. Dove 2019-07-15 /pmc/articles/PMC6642620/ /pubmed/31406465 http://dx.doi.org/10.2147/OTT.S206573 Text en © 2019 Ramaswamy et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Ramaswamy, Rajkumar
Joshi, Nisarg
Khan, Mujtaba A
Siddhara, Seerin
Nanosomal docetaxel lipid suspension based chemotherapy in a pregnant MBC patient – a case report
title Nanosomal docetaxel lipid suspension based chemotherapy in a pregnant MBC patient – a case report
title_full Nanosomal docetaxel lipid suspension based chemotherapy in a pregnant MBC patient – a case report
title_fullStr Nanosomal docetaxel lipid suspension based chemotherapy in a pregnant MBC patient – a case report
title_full_unstemmed Nanosomal docetaxel lipid suspension based chemotherapy in a pregnant MBC patient – a case report
title_short Nanosomal docetaxel lipid suspension based chemotherapy in a pregnant MBC patient – a case report
title_sort nanosomal docetaxel lipid suspension based chemotherapy in a pregnant mbc patient – a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642620/
https://www.ncbi.nlm.nih.gov/pubmed/31406465
http://dx.doi.org/10.2147/OTT.S206573
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AT khanmujtabaa nanosomaldocetaxellipidsuspensionbasedchemotherapyinapregnantmbcpatientacasereport
AT siddharaseerin nanosomaldocetaxellipidsuspensionbasedchemotherapyinapregnantmbcpatientacasereport

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