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Higher Insulin Resistance and Adiposity in Postmenopausal Women With Breast Cancer Treated With Aromatase Inhibitors
CONTEXT: Aromatase deficiency causes obesity and insulin resistance in aromatase knockout mice and humans with rare mutations of the aromatase gene (CYP19). Aromatase inhibitors are a commonly prescribed therapy for postmenopausal breast cancer. OBJECTIVE: We hypothesized that aromatase inhibitors i...
Autores principales: | Gibb, Fraser W, Dixon, J Michael, Clarke, Catriona, Homer, Natalie Z, Faqehi, Abdullah M M, Andrew, Ruth, Walker, Brian R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642666/ https://www.ncbi.nlm.nih.gov/pubmed/30920624 http://dx.doi.org/10.1210/jc.2018-02339 |
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