Automated structure prediction of trans-acyltransferase polyketide synthase products

Bacterial trans-acyltransferase polyketide synthases (trans-AT PKSs) are among the most complex known enzymes from secondary metabolism and are responsible for the biosynthesis of highly diverse bioactive polyketides. However, most of these metabolites remain uncharacterized, since trans-AT PKSs fre...

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Detalles Bibliográficos
Autores principales: Helfrich, Eric J. N., Ueoka, Reiko, Dolev, Alon, Rust, Michael, Meoded, Roy A., Bhushan, Agneya, Califano, Gianmaria, Costa, Rodrigo, Gugger, Muriel, Steinbeck, Christoph, Moreno, Pablo, Piel, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642696/
https://www.ncbi.nlm.nih.gov/pubmed/31308532
http://dx.doi.org/10.1038/s41589-019-0313-7

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