A Rare Case of Hemophagocytic Lymphohistiocytosis in an Adult with Diffuse Large B-Cell Lymphoma

A 71-year-old Indian female presented with a 3-month history of weight loss and fatigue. Further review confirmed a histological diagnosis of diffuse large B-cell lymphoma. Although bone marrow analysis did not reveal hemophagocytosis, she had some clinical and laboratory pointers to hemophagocytic...

Descripción completa

Detalles Bibliográficos
Autores principales: Mbachi, Chimezie, Igwilo, Rita, Flores, Estefania, Chukwujindu, Ezekiel, Mba, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642749/
https://www.ncbi.nlm.nih.gov/pubmed/31360558
http://dx.doi.org/10.1155/2019/7530698
_version_ 1783437030954369024
author Mbachi, Chimezie
Igwilo, Rita
Flores, Estefania
Chukwujindu, Ezekiel
Mba, Benjamin
author_facet Mbachi, Chimezie
Igwilo, Rita
Flores, Estefania
Chukwujindu, Ezekiel
Mba, Benjamin
author_sort Mbachi, Chimezie
collection PubMed
description A 71-year-old Indian female presented with a 3-month history of weight loss and fatigue. Further review confirmed a histological diagnosis of diffuse large B-cell lymphoma. Although bone marrow analysis did not reveal hemophagocytosis, she had some clinical and laboratory pointers to hemophagocytic lymphohistiocytosis (HLH). Her clinical state deteriorated rapidly with development of acute respiratory distress syndrome, diffuse alveolar hemorrhage, and subsequently death.
format Online
Article
Text
id pubmed-6642749
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-66427492019-07-29 A Rare Case of Hemophagocytic Lymphohistiocytosis in an Adult with Diffuse Large B-Cell Lymphoma Mbachi, Chimezie Igwilo, Rita Flores, Estefania Chukwujindu, Ezekiel Mba, Benjamin Case Rep Hematol Case Report A 71-year-old Indian female presented with a 3-month history of weight loss and fatigue. Further review confirmed a histological diagnosis of diffuse large B-cell lymphoma. Although bone marrow analysis did not reveal hemophagocytosis, she had some clinical and laboratory pointers to hemophagocytic lymphohistiocytosis (HLH). Her clinical state deteriorated rapidly with development of acute respiratory distress syndrome, diffuse alveolar hemorrhage, and subsequently death. Hindawi 2019-07-07 /pmc/articles/PMC6642749/ /pubmed/31360558 http://dx.doi.org/10.1155/2019/7530698 Text en Copyright © 2019 Chimezie Mbachi et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Mbachi, Chimezie
Igwilo, Rita
Flores, Estefania
Chukwujindu, Ezekiel
Mba, Benjamin
A Rare Case of Hemophagocytic Lymphohistiocytosis in an Adult with Diffuse Large B-Cell Lymphoma
title A Rare Case of Hemophagocytic Lymphohistiocytosis in an Adult with Diffuse Large B-Cell Lymphoma
title_full A Rare Case of Hemophagocytic Lymphohistiocytosis in an Adult with Diffuse Large B-Cell Lymphoma
title_fullStr A Rare Case of Hemophagocytic Lymphohistiocytosis in an Adult with Diffuse Large B-Cell Lymphoma
title_full_unstemmed A Rare Case of Hemophagocytic Lymphohistiocytosis in an Adult with Diffuse Large B-Cell Lymphoma
title_short A Rare Case of Hemophagocytic Lymphohistiocytosis in an Adult with Diffuse Large B-Cell Lymphoma
title_sort rare case of hemophagocytic lymphohistiocytosis in an adult with diffuse large b-cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642749/
https://www.ncbi.nlm.nih.gov/pubmed/31360558
http://dx.doi.org/10.1155/2019/7530698
work_keys_str_mv AT mbachichimezie ararecaseofhemophagocyticlymphohistiocytosisinanadultwithdiffuselargebcelllymphoma
AT igwilorita ararecaseofhemophagocyticlymphohistiocytosisinanadultwithdiffuselargebcelllymphoma
AT floresestefania ararecaseofhemophagocyticlymphohistiocytosisinanadultwithdiffuselargebcelllymphoma
AT chukwujinduezekiel ararecaseofhemophagocyticlymphohistiocytosisinanadultwithdiffuselargebcelllymphoma
AT mbabenjamin ararecaseofhemophagocyticlymphohistiocytosisinanadultwithdiffuselargebcelllymphoma
AT mbachichimezie rarecaseofhemophagocyticlymphohistiocytosisinanadultwithdiffuselargebcelllymphoma
AT igwilorita rarecaseofhemophagocyticlymphohistiocytosisinanadultwithdiffuselargebcelllymphoma
AT floresestefania rarecaseofhemophagocyticlymphohistiocytosisinanadultwithdiffuselargebcelllymphoma
AT chukwujinduezekiel rarecaseofhemophagocyticlymphohistiocytosisinanadultwithdiffuselargebcelllymphoma
AT mbabenjamin rarecaseofhemophagocyticlymphohistiocytosisinanadultwithdiffuselargebcelllymphoma

Ejemplares similares