Cargando…
Type 2 diabetes is associated with the accumulation of senescent T cells
Type 2 diabetes is a global health priority, given that it is driven, in part, by an ageing population, the role of immune senescence has been overlooked. This is surprising, as the functional impairments of senescent T cells show strong similarities to patients with hyperglycaemia. Immune senescenc...
Autores principales: | Lau, E. Y. M., Carroll, E. C., Callender, L. A., Hood, G. A., Berryman, V., Pattrick, M., Finer, S., Hitman, G. A., Ackland, G. L., Henson, S. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642873/ https://www.ncbi.nlm.nih.gov/pubmed/31251396 http://dx.doi.org/10.1111/cei.13344 |
Ejemplares similares
-
Altered Nutrient Uptake Causes Mitochondrial Dysfunction in Senescent CD8(+) EMRA T Cells During Type 2 Diabetes
por: Callender, Lauren A., et al.
Publicado: (2021) -
Mitochondrial mass governs the extent of human T cell senescence
por: Callender, Lauren A., et al.
Publicado: (2019) -
Human CD8(+)
EMRA T cells display a senescence‐associated secretory phenotype regulated by p38 MAPK
por: Callender, Lauren A., et al.
Publicado: (2017) -
Senescence and Type 2 Diabetic Cardiomyopathy: How Young Can You Die of Old Age?
por: Henson, Sian M., et al.
Publicado: (2021) -
Vitamin B(12) and Folate Markers Are Associated with Insulin Resistance During the Third Trimester of Pregnancy in South Asian Women, Living in the United Kingdom, with Gestational Diabetes and Normal Glucose Tolerance
por: Sobczyńska-Malefora, Agata, et al.
Publicado: (2021)