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Hospital differences in mortality rates after hip fracture surgery in Denmark

BACKGROUND: Thirty-day mortality after hip fracture is widely used when ranking hospital performance, but the reliability of such hospital ranking is seldom calculated. We aimed to quantify the variation in 30-day mortality across hospitals and to determine the hospital general contextual effect for...

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Autores principales: Kristensen, Pia Kjær, Merlo, Juan, Ghith, Nermin, Leckie, George, Johnsen, Søren Paaske
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643065/
https://www.ncbi.nlm.nih.gov/pubmed/31410068
http://dx.doi.org/10.2147/CLEP.S213898
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author Kristensen, Pia Kjær
Merlo, Juan
Ghith, Nermin
Leckie, George
Johnsen, Søren Paaske
author_facet Kristensen, Pia Kjær
Merlo, Juan
Ghith, Nermin
Leckie, George
Johnsen, Søren Paaske
author_sort Kristensen, Pia Kjær
collection PubMed
description BACKGROUND: Thirty-day mortality after hip fracture is widely used when ranking hospital performance, but the reliability of such hospital ranking is seldom calculated. We aimed to quantify the variation in 30-day mortality across hospitals and to determine the hospital general contextual effect for understanding patient differences in 30-day mortality risk. METHODS: Patients aged ≥65 years with an incident hip fracture registered in the Danish Multidisciplinary Fracture Registry between 2007 and 2016 were identified (n=60,004). We estimated unadjusted and patient-mix adjusted risk of 30-day mortality in 32 hospitals. We performed a multilevel analysis of individual heterogeneity and discriminatory accuracy with patients nested within hospitals. We expressed the hospital general contextual effect by the median odds ratio (MOR), the area under the receiver operating characteristics curve and the variance partition coefficient (VPC). RESULTS: The overall 30-day mortality rate was 10%. Patient characteristics including high sociodemographic risk score, underweight, comorbidity, a subtrochanteric fracture, and living at a nursing home were strong predictors of 30-day mortality (area under the curve=0.728). The adjusted differences between hospital averages in 30-day mortality varied from 5% to 9% across the 32 hospitals, which correspond to a MOR of 1.18 (95% CI: 1.12–1.25). However, the hospital general context effect was low, as the VPC was below 1% and adding the hospital level to a single-level model with adjustment for patient-mix increased the area under the receiver operating characteristics curve by only 0.004 units. CONCLUSIONS: Only minor hospital differences were found in 30-day mortality after hip fracture. Mortality after hip fracture needs to be lowered in Denmark but possible interventions should be patient oriented and universal rather than focused on specific hospitals.
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spelling pubmed-66430652019-08-13 Hospital differences in mortality rates after hip fracture surgery in Denmark Kristensen, Pia Kjær Merlo, Juan Ghith, Nermin Leckie, George Johnsen, Søren Paaske Clin Epidemiol Original Research BACKGROUND: Thirty-day mortality after hip fracture is widely used when ranking hospital performance, but the reliability of such hospital ranking is seldom calculated. We aimed to quantify the variation in 30-day mortality across hospitals and to determine the hospital general contextual effect for understanding patient differences in 30-day mortality risk. METHODS: Patients aged ≥65 years with an incident hip fracture registered in the Danish Multidisciplinary Fracture Registry between 2007 and 2016 were identified (n=60,004). We estimated unadjusted and patient-mix adjusted risk of 30-day mortality in 32 hospitals. We performed a multilevel analysis of individual heterogeneity and discriminatory accuracy with patients nested within hospitals. We expressed the hospital general contextual effect by the median odds ratio (MOR), the area under the receiver operating characteristics curve and the variance partition coefficient (VPC). RESULTS: The overall 30-day mortality rate was 10%. Patient characteristics including high sociodemographic risk score, underweight, comorbidity, a subtrochanteric fracture, and living at a nursing home were strong predictors of 30-day mortality (area under the curve=0.728). The adjusted differences between hospital averages in 30-day mortality varied from 5% to 9% across the 32 hospitals, which correspond to a MOR of 1.18 (95% CI: 1.12–1.25). However, the hospital general context effect was low, as the VPC was below 1% and adding the hospital level to a single-level model with adjustment for patient-mix increased the area under the receiver operating characteristics curve by only 0.004 units. CONCLUSIONS: Only minor hospital differences were found in 30-day mortality after hip fracture. Mortality after hip fracture needs to be lowered in Denmark but possible interventions should be patient oriented and universal rather than focused on specific hospitals. Dove 2019-07-16 /pmc/articles/PMC6643065/ /pubmed/31410068 http://dx.doi.org/10.2147/CLEP.S213898 Text en © 2019 Kristensen et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Kristensen, Pia Kjær
Merlo, Juan
Ghith, Nermin
Leckie, George
Johnsen, Søren Paaske
Hospital differences in mortality rates after hip fracture surgery in Denmark
title Hospital differences in mortality rates after hip fracture surgery in Denmark
title_full Hospital differences in mortality rates after hip fracture surgery in Denmark
title_fullStr Hospital differences in mortality rates after hip fracture surgery in Denmark
title_full_unstemmed Hospital differences in mortality rates after hip fracture surgery in Denmark
title_short Hospital differences in mortality rates after hip fracture surgery in Denmark
title_sort hospital differences in mortality rates after hip fracture surgery in denmark
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643065/
https://www.ncbi.nlm.nih.gov/pubmed/31410068
http://dx.doi.org/10.2147/CLEP.S213898
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