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Metabolic effects of Ramadan fasting in patients at high risk of cardiovascular diseases

BACKGROUND AND AIM: The effects of Ramadan fasting on health are a little controversial. The present study is aimed at evaluating the metabolic effects on a group of 517 patients with ≥2 cardiovascular risk factors over a period running from 2012 to 2014. METHODS: Each patient was assessed at three...

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Autores principales: Beltaief, K, Bouida, W, Trabelsi, I, Baccouche, H, Sassi, M, Dridi, Z, Chakroun, T, Hellara, I, Boukef, R, Hassine, M, Addad, F, Razgallah, R, Khochtali, I, Nouira, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643153/
https://www.ncbi.nlm.nih.gov/pubmed/31410047
http://dx.doi.org/10.2147/IJGM.S172341
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author Beltaief, K
Bouida, W
Trabelsi, I
Baccouche, H
Sassi, M
Dridi, Z
Chakroun, T
Hellara, I
Boukef, R
Hassine, M
Addad, F
Razgallah, R
Khochtali, I
Nouira, S
author_facet Beltaief, K
Bouida, W
Trabelsi, I
Baccouche, H
Sassi, M
Dridi, Z
Chakroun, T
Hellara, I
Boukef, R
Hassine, M
Addad, F
Razgallah, R
Khochtali, I
Nouira, S
author_sort Beltaief, K
collection PubMed
description BACKGROUND AND AIM: The effects of Ramadan fasting on health are a little controversial. The present study is aimed at evaluating the metabolic effects on a group of 517 patients with ≥2 cardiovascular risk factors over a period running from 2012 to 2014. METHODS: Each patient was assessed at three visits: before, during, and after Ramadan. Demographical, clinical and biological tests were performed at each visit. RESULTS: Metabolically, we noted a significant and discrete rise in blood glucose level (+1.2 mmol/L), triglycerides (+0.3 mmol/L), cholesterol (+0.12 mmol/L) and creatinine (+3 µmol/L) during Ramadan. These disturbances decreased significantly after Ramadan. The same variations were observed among diabetics (n=323). However, there was a significant decrease in HbA1c after Ramadan (9.0% vs 7.6%, p<0.001). Our findings also revealed there was no significant correlation between variations of metabolic parameters and dietary intake. No acute metabolic incidents were reported during the study period. CONCLUSION: The current study showed that Ramadan is responsible for a transient but well tolerated disturbance of metabolic parameters followed by a significant post-Ramadan improvement. These changes did not seem to be directly related to dietary intake.
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spelling pubmed-66431532019-08-13 Metabolic effects of Ramadan fasting in patients at high risk of cardiovascular diseases Beltaief, K Bouida, W Trabelsi, I Baccouche, H Sassi, M Dridi, Z Chakroun, T Hellara, I Boukef, R Hassine, M Addad, F Razgallah, R Khochtali, I Nouira, S Int J Gen Med Original Research BACKGROUND AND AIM: The effects of Ramadan fasting on health are a little controversial. The present study is aimed at evaluating the metabolic effects on a group of 517 patients with ≥2 cardiovascular risk factors over a period running from 2012 to 2014. METHODS: Each patient was assessed at three visits: before, during, and after Ramadan. Demographical, clinical and biological tests were performed at each visit. RESULTS: Metabolically, we noted a significant and discrete rise in blood glucose level (+1.2 mmol/L), triglycerides (+0.3 mmol/L), cholesterol (+0.12 mmol/L) and creatinine (+3 µmol/L) during Ramadan. These disturbances decreased significantly after Ramadan. The same variations were observed among diabetics (n=323). However, there was a significant decrease in HbA1c after Ramadan (9.0% vs 7.6%, p<0.001). Our findings also revealed there was no significant correlation between variations of metabolic parameters and dietary intake. No acute metabolic incidents were reported during the study period. CONCLUSION: The current study showed that Ramadan is responsible for a transient but well tolerated disturbance of metabolic parameters followed by a significant post-Ramadan improvement. These changes did not seem to be directly related to dietary intake. Dove 2019-07-15 /pmc/articles/PMC6643153/ /pubmed/31410047 http://dx.doi.org/10.2147/IJGM.S172341 Text en © 2019 Beltaief et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Beltaief, K
Bouida, W
Trabelsi, I
Baccouche, H
Sassi, M
Dridi, Z
Chakroun, T
Hellara, I
Boukef, R
Hassine, M
Addad, F
Razgallah, R
Khochtali, I
Nouira, S
Metabolic effects of Ramadan fasting in patients at high risk of cardiovascular diseases
title Metabolic effects of Ramadan fasting in patients at high risk of cardiovascular diseases
title_full Metabolic effects of Ramadan fasting in patients at high risk of cardiovascular diseases
title_fullStr Metabolic effects of Ramadan fasting in patients at high risk of cardiovascular diseases
title_full_unstemmed Metabolic effects of Ramadan fasting in patients at high risk of cardiovascular diseases
title_short Metabolic effects of Ramadan fasting in patients at high risk of cardiovascular diseases
title_sort metabolic effects of ramadan fasting in patients at high risk of cardiovascular diseases
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643153/
https://www.ncbi.nlm.nih.gov/pubmed/31410047
http://dx.doi.org/10.2147/IJGM.S172341
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