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Comparison of Serum Ykl-40 and Ischemia Modified Albulmin Levels Between Pregnant Women with Hyperemesis Gravidarum and Normal Pregnant Women
INTRODUCTION: The etiopathogenesis of HG is still unclear. AIM: The aim of this study was to investigate the levels of YKL-40 protein as an inflammatory marker and evaluate the levels of IMA as an oxidative marker in hyperemesis gravidarum women. MATERIALS AND METHODS: Totally 35 patients with hyper...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academy of Medical Sciences of Bosnia and Herzegovina
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643323/ https://www.ncbi.nlm.nih.gov/pubmed/31391695 http://dx.doi.org/10.5455/medarh.2019.73.97-100 |
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author | Bulanık, Murat Sağsöz, Nevin Sayan, Cemile Dayangan Yeral, Mahmut İlkin Kısa, Üçler |
author_facet | Bulanık, Murat Sağsöz, Nevin Sayan, Cemile Dayangan Yeral, Mahmut İlkin Kısa, Üçler |
author_sort | Bulanık, Murat |
collection | PubMed |
description | INTRODUCTION: The etiopathogenesis of HG is still unclear. AIM: The aim of this study was to investigate the levels of YKL-40 protein as an inflammatory marker and evaluate the levels of IMA as an oxidative marker in hyperemesis gravidarum women. MATERIALS AND METHODS: Totally 35 patients with hyperemesis gravidarum and 35 healthy pregnants were included in the study. Singleton pregnancies between 6+0 week and 13+6 weeks of gestation, with normal fetal anatomy were included in the study. Complete blood count, complete urine analyze, biochemical tests and thyroid function tests were done. RESULTS: There was no significant difference between groups for demographical features (age, gravidity, gestational age, body mass index). Also, there was no statistically significant difference between groups for IMA levels (p>0.05). The median level of YKL-40 was higher in pregnants with hyperemesis gravidarum than normal pregnants but the difference was not statistically significance (p>0.05). CONCLUSION: Further comprehensive studies with more number of patients are needed to show the efficacy of YKL-40 and IMA levels for predicting hyperemesis gravidarum and even monitoring of the treatment. |
format | Online Article Text |
id | pubmed-6643323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Academy of Medical Sciences of Bosnia and Herzegovina |
record_format | MEDLINE/PubMed |
spelling | pubmed-66433232019-08-07 Comparison of Serum Ykl-40 and Ischemia Modified Albulmin Levels Between Pregnant Women with Hyperemesis Gravidarum and Normal Pregnant Women Bulanık, Murat Sağsöz, Nevin Sayan, Cemile Dayangan Yeral, Mahmut İlkin Kısa, Üçler Med Arch Original Paper INTRODUCTION: The etiopathogenesis of HG is still unclear. AIM: The aim of this study was to investigate the levels of YKL-40 protein as an inflammatory marker and evaluate the levels of IMA as an oxidative marker in hyperemesis gravidarum women. MATERIALS AND METHODS: Totally 35 patients with hyperemesis gravidarum and 35 healthy pregnants were included in the study. Singleton pregnancies between 6+0 week and 13+6 weeks of gestation, with normal fetal anatomy were included in the study. Complete blood count, complete urine analyze, biochemical tests and thyroid function tests were done. RESULTS: There was no significant difference between groups for demographical features (age, gravidity, gestational age, body mass index). Also, there was no statistically significant difference between groups for IMA levels (p>0.05). The median level of YKL-40 was higher in pregnants with hyperemesis gravidarum than normal pregnants but the difference was not statistically significance (p>0.05). CONCLUSION: Further comprehensive studies with more number of patients are needed to show the efficacy of YKL-40 and IMA levels for predicting hyperemesis gravidarum and even monitoring of the treatment. Academy of Medical Sciences of Bosnia and Herzegovina 2019-04 /pmc/articles/PMC6643323/ /pubmed/31391695 http://dx.doi.org/10.5455/medarh.2019.73.97-100 Text en © 2019 Murat Bulanık, Nevin Sağsöz, Cemile Dayangan Sayan, Mahmut İlkin Yeral, Üçler Kısa http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Paper Bulanık, Murat Sağsöz, Nevin Sayan, Cemile Dayangan Yeral, Mahmut İlkin Kısa, Üçler Comparison of Serum Ykl-40 and Ischemia Modified Albulmin Levels Between Pregnant Women with Hyperemesis Gravidarum and Normal Pregnant Women |
title | Comparison of Serum Ykl-40 and Ischemia Modified Albulmin Levels Between Pregnant Women with Hyperemesis Gravidarum and Normal Pregnant Women |
title_full | Comparison of Serum Ykl-40 and Ischemia Modified Albulmin Levels Between Pregnant Women with Hyperemesis Gravidarum and Normal Pregnant Women |
title_fullStr | Comparison of Serum Ykl-40 and Ischemia Modified Albulmin Levels Between Pregnant Women with Hyperemesis Gravidarum and Normal Pregnant Women |
title_full_unstemmed | Comparison of Serum Ykl-40 and Ischemia Modified Albulmin Levels Between Pregnant Women with Hyperemesis Gravidarum and Normal Pregnant Women |
title_short | Comparison of Serum Ykl-40 and Ischemia Modified Albulmin Levels Between Pregnant Women with Hyperemesis Gravidarum and Normal Pregnant Women |
title_sort | comparison of serum ykl-40 and ischemia modified albulmin levels between pregnant women with hyperemesis gravidarum and normal pregnant women |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643323/ https://www.ncbi.nlm.nih.gov/pubmed/31391695 http://dx.doi.org/10.5455/medarh.2019.73.97-100 |
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