Cargando…
Clinical Characteristics and Outcome of Malignant Eyelid Tumors: A Five-Year Retrospective Study
INTRODUCTION: To the best of our knowledge, this is the first study about malignant eyelid tumors in the region of Tuzla, Bosnia and Herzegovina, and it shows similar results comparing with other countries (the annual incidence of eyelid tumors in Tuzla region is about 3.73/100 000 population). Mali...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academy of Medical Sciences of Bosnia and Herzegovina
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643352/ https://www.ncbi.nlm.nih.gov/pubmed/31402806 http://dx.doi.org/10.5455/medarh.2019.73.209-212 |
_version_ | 1783437111447257088 |
---|---|
author | Burgic, Mufid Iljazovic, Ermina Vodencarevic, Amra Nadarevic Burgic, Musfaha Rifatbegovic, Adi Mujkanovic, Amer Halilbasic, Meliha Sinanovic, Mersiha |
author_facet | Burgic, Mufid Iljazovic, Ermina Vodencarevic, Amra Nadarevic Burgic, Musfaha Rifatbegovic, Adi Mujkanovic, Amer Halilbasic, Meliha Sinanovic, Mersiha |
author_sort | Burgic, Mufid |
collection | PubMed |
description | INTRODUCTION: To the best of our knowledge, this is the first study about malignant eyelid tumors in the region of Tuzla, Bosnia and Herzegovina, and it shows similar results comparing with other countries (the annual incidence of eyelid tumors in Tuzla region is about 3.73/100 000 population). Malignant eyelid tumors are relatively uncommon, but potentially fatal disease. However, if detected early and treated adequately, the prognosis is generally excellent. AIM: The aim of this study was the clinical and microscopical analysis of malignant eyelid tumors in treated patients, the presentation of surgical treatment and reconstructive methods of eyelid tumors. METHODS: This retrospective study included 60 patients surgically treated at the University Clinical Center Tuzla from January 2012 to December 2016, who were initially diagnosed with malignant eyelid tumors in accordance to the final results obtained by histological examination of excised lesions. RESULTS: In the group of malignant tumors, the most common tumors were BCC (85%), which were predominantly found on the lower eyelids (92.16%) and showed female predominance (51.06%). SCC was the second most common eyelid malignancy (15%) and showed a predilection for the lower eyelid involvement and male predominance (55.56%). Tumors up to 2 cm in diameter (clinical stage T1) were found in 78.33% of cases, 95.74% of which with radical excision, while 4.26% with non-radical excision. CONCLUSION: Treatment by complete excision with histological confirmation of tumor clearance is recommended. Perineural spread is an adverse prognostic sign, which may require postoperative radiotherapy. Orbital invasion is a rare complication but, if recognized early, it can be treated effectively with exenteration. Because presentation varies and histological examination is required for accurate diagnosis, any suspicious lesion occurring on the eyelids should be excised or biopsied. All patients with malignant tumors should be advised of the risk of recurrent or new tumors and encouraged to attend lifelong follow up. |
format | Online Article Text |
id | pubmed-6643352 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Academy of Medical Sciences of Bosnia and Herzegovina |
record_format | MEDLINE/PubMed |
spelling | pubmed-66433522019-08-09 Clinical Characteristics and Outcome of Malignant Eyelid Tumors: A Five-Year Retrospective Study Burgic, Mufid Iljazovic, Ermina Vodencarevic, Amra Nadarevic Burgic, Musfaha Rifatbegovic, Adi Mujkanovic, Amer Halilbasic, Meliha Sinanovic, Mersiha Med Arch Professional Paper INTRODUCTION: To the best of our knowledge, this is the first study about malignant eyelid tumors in the region of Tuzla, Bosnia and Herzegovina, and it shows similar results comparing with other countries (the annual incidence of eyelid tumors in Tuzla region is about 3.73/100 000 population). Malignant eyelid tumors are relatively uncommon, but potentially fatal disease. However, if detected early and treated adequately, the prognosis is generally excellent. AIM: The aim of this study was the clinical and microscopical analysis of malignant eyelid tumors in treated patients, the presentation of surgical treatment and reconstructive methods of eyelid tumors. METHODS: This retrospective study included 60 patients surgically treated at the University Clinical Center Tuzla from January 2012 to December 2016, who were initially diagnosed with malignant eyelid tumors in accordance to the final results obtained by histological examination of excised lesions. RESULTS: In the group of malignant tumors, the most common tumors were BCC (85%), which were predominantly found on the lower eyelids (92.16%) and showed female predominance (51.06%). SCC was the second most common eyelid malignancy (15%) and showed a predilection for the lower eyelid involvement and male predominance (55.56%). Tumors up to 2 cm in diameter (clinical stage T1) were found in 78.33% of cases, 95.74% of which with radical excision, while 4.26% with non-radical excision. CONCLUSION: Treatment by complete excision with histological confirmation of tumor clearance is recommended. Perineural spread is an adverse prognostic sign, which may require postoperative radiotherapy. Orbital invasion is a rare complication but, if recognized early, it can be treated effectively with exenteration. Because presentation varies and histological examination is required for accurate diagnosis, any suspicious lesion occurring on the eyelids should be excised or biopsied. All patients with malignant tumors should be advised of the risk of recurrent or new tumors and encouraged to attend lifelong follow up. Academy of Medical Sciences of Bosnia and Herzegovina 2019-06 /pmc/articles/PMC6643352/ /pubmed/31402806 http://dx.doi.org/10.5455/medarh.2019.73.209-212 Text en © 2019 Mufid Burgic, Ermina Iljazovic, Amra Nadarevic Vodencarevic, Musfaha Burgic, Adi Rifatbegovic, Amer Mujkanovic, Meliha Halilbasic, Mersiha Sinanovic http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Professional Paper Burgic, Mufid Iljazovic, Ermina Vodencarevic, Amra Nadarevic Burgic, Musfaha Rifatbegovic, Adi Mujkanovic, Amer Halilbasic, Meliha Sinanovic, Mersiha Clinical Characteristics and Outcome of Malignant Eyelid Tumors: A Five-Year Retrospective Study |
title | Clinical Characteristics and Outcome of Malignant Eyelid Tumors: A Five-Year Retrospective Study |
title_full | Clinical Characteristics and Outcome of Malignant Eyelid Tumors: A Five-Year Retrospective Study |
title_fullStr | Clinical Characteristics and Outcome of Malignant Eyelid Tumors: A Five-Year Retrospective Study |
title_full_unstemmed | Clinical Characteristics and Outcome of Malignant Eyelid Tumors: A Five-Year Retrospective Study |
title_short | Clinical Characteristics and Outcome of Malignant Eyelid Tumors: A Five-Year Retrospective Study |
title_sort | clinical characteristics and outcome of malignant eyelid tumors: a five-year retrospective study |
topic | Professional Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643352/ https://www.ncbi.nlm.nih.gov/pubmed/31402806 http://dx.doi.org/10.5455/medarh.2019.73.209-212 |
work_keys_str_mv | AT burgicmufid clinicalcharacteristicsandoutcomeofmalignanteyelidtumorsafiveyearretrospectivestudy AT iljazovicermina clinicalcharacteristicsandoutcomeofmalignanteyelidtumorsafiveyearretrospectivestudy AT vodencarevicamranadarevic clinicalcharacteristicsandoutcomeofmalignanteyelidtumorsafiveyearretrospectivestudy AT burgicmusfaha clinicalcharacteristicsandoutcomeofmalignanteyelidtumorsafiveyearretrospectivestudy AT rifatbegovicadi clinicalcharacteristicsandoutcomeofmalignanteyelidtumorsafiveyearretrospectivestudy AT mujkanovicamer clinicalcharacteristicsandoutcomeofmalignanteyelidtumorsafiveyearretrospectivestudy AT halilbasicmeliha clinicalcharacteristicsandoutcomeofmalignanteyelidtumorsafiveyearretrospectivestudy AT sinanovicmersiha clinicalcharacteristicsandoutcomeofmalignanteyelidtumorsafiveyearretrospectivestudy |