A Compound AC1Q3QWB Selectively Disrupts HOTAIR-Mediated Recruitment of PRC2 and Enhances Cancer Therapy of DZNep

Over 20% of cancer 'driver' genes encode chromatin regulators. Long noncoding RNAs (lincRNAs), which are dysregulated in various cancers, play a critical role in chromatin dynamics and gene regulation by interacting with key epigenetic regulators. It has been previously reported that the l...

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Detalles Bibliográficos
Autores principales: Li, Yansheng, Ren, Yu, Wang, Yunfei, Tan, Yanli, Wang, Qixue, Cai, Jinquan, Zhou, Junhu, Yang, Chao, Zhao, Kai, Yi, Kaikai, Jin, Weili, Wang, Lin, Liu, Mingyang, Yang, Jingxuan, Li, Min, Kang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643429/
https://www.ncbi.nlm.nih.gov/pubmed/31367244
http://dx.doi.org/10.7150/thno.35188

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