Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis

Background: Tobacco smoke (TS) critically contributes to the development of lung cancer; however, the underlying molecular mechanisms remain unclear. The induction of cancer stem cells (CSCs) by TS represents an early event in tumor initiation. The lung cancer-related gene ΔNp63α is highly expressed...

Descripción completa

Detalles Bibliográficos
Autores principales: Xie, Chunfeng, Zhu, Jianyun, Jiang, Ye, Chen, Jiaqi, Wang, Xueqi, Geng, Shanshan, Wu, Jieshu, Zhong, Caiyun, Li, Xiaoting, Meng, Zili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643434/
https://www.ncbi.nlm.nih.gov/pubmed/31367260
http://dx.doi.org/10.7150/thno.33812

Ejemplares similares

Ejemplares similares