Employing Macrophage-Derived Microvesicle for Kidney-Targeted Delivery of Dexamethasone: An Efficient Therapeutic Strategy against Renal Inflammation and Fibrosis

Although glucocorticoids are the mainstays in the treatment of renal diseases for decades, the dose dependent side effects have largely restricted their clinical use. Microvesicles (MVs) are small lipid-based membrane-bound particles generated by virtually all cells. Here we show that RAW 264.7 macr...

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Detalles Bibliográficos
Autores principales: Tang, Tao-Tao, Lv, Lin-Li, Wang, Bin, Cao, Jing-Yuan, Feng, Ye, Li, Zuo-Lin, Wu, Min, Wang, Feng-Mei, Wen, Yi, Zhou, Le-Ting, Ni, Hai-Feng, Chen, Ping-Sheng, Gu, Ning, Crowley, Steven D., Liu, Bi-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643445/
https://www.ncbi.nlm.nih.gov/pubmed/31367254
http://dx.doi.org/10.7150/thno.33520

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