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Folding Molecular Dynamics Simulation of a gp41-Derived Peptide Reconcile Divergent Structure Determinations

[Image: see text] T-20 peptide is the first FDA-approved fusion inhibitor against AIDS/HIV-1 gp41 protein. Part of it, the gp41[659–671] peptide, that contains the complete epitope for the neutralizing 2F5 monoclonal antibody, has been found experimentally in a number of divergent structures. Herein...

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Detalles Bibliográficos
Autores principales: Georgoulia, Panagiota S., Glykos, Nicholas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643504/
https://www.ncbi.nlm.nih.gov/pubmed/31458149
http://dx.doi.org/10.1021/acsomega.8b01579

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