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Comparative Computational Approach To Study Enzyme Reactions Using QM and QM-MM Methods
[Image: see text] Choline oxidase catalyzes oxidation of choline into glycine betaine through a two-step reaction pathway employing flavin as the cofactor. On the light of kinetic studies, it is proposed that a hydride ion is transferred from α-carbon of choline/hydrated-betaine aldehyde to the N5 p...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643517/ https://www.ncbi.nlm.nih.gov/pubmed/31458147 http://dx.doi.org/10.1021/acsomega.8b02638 |