Highly Efficient and Practical N-Heterocyclic Carbene Organocatalyzed Chemoselective N(1)/C(3)-Functionalization of Isatins with Green Chemistry Principles

[Image: see text] Ecofriendly N-heterocyclic carbene (NHC) organocatalysis can control the N(1)-functionalization (aza-Michael addition) and C(3)-functionalization (Morita–Baylis–Hillman reaction, MBH) of isatins in the absence of (1) a protecting group, (2) a stoichiometric reagent, and (3) heat en...

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Detalles Bibliográficos
Autores principales: Mudithanapelli, Chandrashekar, Vasam, Chandra Sekhar, Vadde, Ravinder, Kim, Mi-hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643579/
https://www.ncbi.nlm.nih.gov/pubmed/31458364
http://dx.doi.org/10.1021/acsomega.8b02361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643579/
https://www.ncbi.nlm.nih.gov/pubmed/31458364
http://dx.doi.org/10.1021/acsomega.8b02361

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