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Cryptolepine, the Main Alkaloid of the Antimalarial Cryptolepis sanguinolenta (Lindl.) Schlechter, Induces Malformations in Zebrafish Embryos
BACKGROUND: Previous studies on cryptolepine, the antimalarial and cytotoxic alkaloid of Cryptolepis sanguinolenta, showed that it preferentially accumulates in rapidly proliferating cells and melanin-containing tissues. Subsequently, we demonstrated that cryptolepine was toxic to murine embryos in...
Autores principales: | Mensah, Kwesi Boadu, Benneh, Charles, Forkuo, Arnold Donkor, Ansah, Charles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644280/ https://www.ncbi.nlm.nih.gov/pubmed/31360547 http://dx.doi.org/10.1155/2019/7076986 |
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