Base-Catalyzed 1,6-Conjugate Addition of Nitroalkanes to p-Quinone Methides under Continuous Flow

[Image: see text] A mild base-catalyzed protocol for the synthesis of substituted nitroalkane derivatives has been developed under continuous flow using a microreaction technique. This transformation basically involves the 1,6-conjugate addition of nitroalkanes to p-quinone methides, leading to the...

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Detalles Bibliográficos
Autores principales: Pandey, Rajat, Anand, Ramasamy Vijaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644449/
https://www.ncbi.nlm.nih.gov/pubmed/31458092
http://dx.doi.org/10.1021/acsomega.8b01971
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author Pandey, Rajat
Anand, Ramasamy Vijaya
author_facet Pandey, Rajat
Anand, Ramasamy Vijaya
author_sort Pandey, Rajat
collection PubMed
description [Image: see text] A mild base-catalyzed protocol for the synthesis of substituted nitroalkane derivatives has been developed under continuous flow using a microreaction technique. This transformation basically involves the 1,6-conjugate addition of nitroalkanes to p-quinone methides, leading to the substituted nitroalkanes in good to excellent yields.
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spelling pubmed-66444492019-08-27 Base-Catalyzed 1,6-Conjugate Addition of Nitroalkanes to p-Quinone Methides under Continuous Flow Pandey, Rajat Anand, Ramasamy Vijaya ACS Omega [Image: see text] A mild base-catalyzed protocol for the synthesis of substituted nitroalkane derivatives has been developed under continuous flow using a microreaction technique. This transformation basically involves the 1,6-conjugate addition of nitroalkanes to p-quinone methides, leading to the substituted nitroalkanes in good to excellent yields. American Chemical Society 2018-10-24 /pmc/articles/PMC6644449/ /pubmed/31458092 http://dx.doi.org/10.1021/acsomega.8b01971 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Pandey, Rajat
Anand, Ramasamy Vijaya
Base-Catalyzed 1,6-Conjugate Addition of Nitroalkanes to p-Quinone Methides under Continuous Flow
title Base-Catalyzed 1,6-Conjugate Addition of Nitroalkanes to p-Quinone Methides under Continuous Flow
title_full Base-Catalyzed 1,6-Conjugate Addition of Nitroalkanes to p-Quinone Methides under Continuous Flow
title_fullStr Base-Catalyzed 1,6-Conjugate Addition of Nitroalkanes to p-Quinone Methides under Continuous Flow
title_full_unstemmed Base-Catalyzed 1,6-Conjugate Addition of Nitroalkanes to p-Quinone Methides under Continuous Flow
title_short Base-Catalyzed 1,6-Conjugate Addition of Nitroalkanes to p-Quinone Methides under Continuous Flow
title_sort base-catalyzed 1,6-conjugate addition of nitroalkanes to p-quinone methides under continuous flow
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644449/
https://www.ncbi.nlm.nih.gov/pubmed/31458092
http://dx.doi.org/10.1021/acsomega.8b01971
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