The Inflammasome Adaptor ASC Intrinsically Limits CD4(+) T-Cell Proliferation to Help Maintain Intestinal Homeostasis

The inflammasome is a multi-protein complex that mediates proteolytic cleavage and release of the pro-inflammatory cytokines IL-1β and IL-18, and pyroptosis—a form of cell death induced by various pathogenic bacteria. Apoptosis-associated speck-like protein containing a CARD (ASC) has a pivotal role...

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Detalles Bibliográficos
Autores principales: Javanmard Khameneh, Hanif, Leong, Keith Weng Kit, Mencarelli, Andrea, Vacca, Maurizio, Mambwe, Bezaleel, Neo, Kurt, Tay, Alice, Zolezzi, Francesca, Lee, Bernett, Mortellaro, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644529/
https://www.ncbi.nlm.nih.gov/pubmed/31379813
http://dx.doi.org/10.3389/fimmu.2019.01566

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