Chiral Pentacarboxycyclopentadiene-Based Brønsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles

[Image: see text] Enantioselective desymmetrization of meso-epoxides by 2-mercaptobenzothiazoles was realized by using the pentacarboxycyclopentadiene-based chiral Brønsted acid in combination of N-isopropylaniline as amine additive to give up to 90.5:9.5 er of the ring opening products.

Detalles Bibliográficos
Autores principales: Yuan, Chao, Li, Jun, Li, Pingfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644688/
https://www.ncbi.nlm.nih.gov/pubmed/31458851
http://dx.doi.org/10.1021/acsomega.8b01207
_version_ 1783437308993732608
author Yuan, Chao
Li, Jun
Li, Pingfan
author_facet Yuan, Chao
Li, Jun
Li, Pingfan
author_sort Yuan, Chao
collection PubMed
description [Image: see text] Enantioselective desymmetrization of meso-epoxides by 2-mercaptobenzothiazoles was realized by using the pentacarboxycyclopentadiene-based chiral Brønsted acid in combination of N-isopropylaniline as amine additive to give up to 90.5:9.5 er of the ring opening products.
format Online
Article
Text
id pubmed-6644688
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-66446882019-08-27 Chiral Pentacarboxycyclopentadiene-Based Brønsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles Yuan, Chao Li, Jun Li, Pingfan ACS Omega [Image: see text] Enantioselective desymmetrization of meso-epoxides by 2-mercaptobenzothiazoles was realized by using the pentacarboxycyclopentadiene-based chiral Brønsted acid in combination of N-isopropylaniline as amine additive to give up to 90.5:9.5 er of the ring opening products. American Chemical Society 2018-06-25 /pmc/articles/PMC6644688/ /pubmed/31458851 http://dx.doi.org/10.1021/acsomega.8b01207 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Yuan, Chao
Li, Jun
Li, Pingfan
Chiral Pentacarboxycyclopentadiene-Based Brønsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles
title Chiral Pentacarboxycyclopentadiene-Based Brønsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles
title_full Chiral Pentacarboxycyclopentadiene-Based Brønsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles
title_fullStr Chiral Pentacarboxycyclopentadiene-Based Brønsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles
title_full_unstemmed Chiral Pentacarboxycyclopentadiene-Based Brønsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles
title_short Chiral Pentacarboxycyclopentadiene-Based Brønsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles
title_sort chiral pentacarboxycyclopentadiene-based brønsted acid-catalyzed enantioselective desymmetrization of meso-epoxides by 2-mercaptobenzothiazoles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644688/
https://www.ncbi.nlm.nih.gov/pubmed/31458851
http://dx.doi.org/10.1021/acsomega.8b01207
work_keys_str_mv AT yuanchao chiralpentacarboxycyclopentadienebasedbrønstedacidcatalyzedenantioselectivedesymmetrizationofmesoepoxidesby2mercaptobenzothiazoles
AT lijun chiralpentacarboxycyclopentadienebasedbrønstedacidcatalyzedenantioselectivedesymmetrizationofmesoepoxidesby2mercaptobenzothiazoles
AT lipingfan chiralpentacarboxycyclopentadienebasedbrønstedacidcatalyzedenantioselectivedesymmetrizationofmesoepoxidesby2mercaptobenzothiazoles

Ejemplares similares