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APTES Duality and Nanopore Seed Regulation in Homogeneous and Nanoscale-Controlled Reduction of Ag Shell on SiO(2) Microparticle for Quantifiable Single Particle SERS

[Image: see text] Noble-metal nanoparticles size and packing density are critical for sensitive surface-enhanced Raman scattering (SERS) and controlled preparation of such films required to achieve reproducibility. Provided that they are made reliable, Ag shell on SiO(2) microscopic particles (Ag/Si...

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Autores principales: Rice, Daragh, Mouras, Rabah, Gleeson, Matthew, Liu, Ning, Tofail, Syed A. M., Soulimane, Tewfik, Silien, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644844/
https://www.ncbi.nlm.nih.gov/pubmed/31458023
http://dx.doi.org/10.1021/acsomega.8b01247
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author Rice, Daragh
Mouras, Rabah
Gleeson, Matthew
Liu, Ning
Tofail, Syed A. M.
Soulimane, Tewfik
Silien, Christophe
author_facet Rice, Daragh
Mouras, Rabah
Gleeson, Matthew
Liu, Ning
Tofail, Syed A. M.
Soulimane, Tewfik
Silien, Christophe
author_sort Rice, Daragh
collection PubMed
description [Image: see text] Noble-metal nanoparticles size and packing density are critical for sensitive surface-enhanced Raman scattering (SERS) and controlled preparation of such films required to achieve reproducibility. Provided that they are made reliable, Ag shell on SiO(2) microscopic particles (Ag/SiO(2)) are promising candidates for lab-on-a-bead analytical measurements of low analyte concentration in liquid specimen. Here, we selected nanoporous silica microparticles as a substrate for reduction of AgNO(3) with 3-aminopropyltriethoxysilane (APTES). In a single preparation step, homogeneous and continuous films of Ag nanoparticles are formed on SiO(2) surfaces with equimolar concentration of APTES and silver nitrate in ethanol. It is discussed that amine and silane moieties in APTES contribute first to an efficient reduction on the silica and second to capping the Ag nanoparticles. The high density and homogeneity of nanoparticle nucleation is further regulated by the nanoporosity of the silica. The Ag/SiO(2) microparticles were tested for SERS using self-assembled 4-aminothiophenol monolayers, and an enhancement factor of ca. 2 × 10(6) is measured. Importantly, the SERS relative standard deviation is 36% when a single microparticle is considered and drops to 11% when sets of 10 microparticles are considered. As prepared, the microparticles are highly suitable for state-of-the-art quantitative lab-on-a-bead interrogation of specimens.
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spelling pubmed-66448442019-08-27 APTES Duality and Nanopore Seed Regulation in Homogeneous and Nanoscale-Controlled Reduction of Ag Shell on SiO(2) Microparticle for Quantifiable Single Particle SERS Rice, Daragh Mouras, Rabah Gleeson, Matthew Liu, Ning Tofail, Syed A. M. Soulimane, Tewfik Silien, Christophe ACS Omega [Image: see text] Noble-metal nanoparticles size and packing density are critical for sensitive surface-enhanced Raman scattering (SERS) and controlled preparation of such films required to achieve reproducibility. Provided that they are made reliable, Ag shell on SiO(2) microscopic particles (Ag/SiO(2)) are promising candidates for lab-on-a-bead analytical measurements of low analyte concentration in liquid specimen. Here, we selected nanoporous silica microparticles as a substrate for reduction of AgNO(3) with 3-aminopropyltriethoxysilane (APTES). In a single preparation step, homogeneous and continuous films of Ag nanoparticles are formed on SiO(2) surfaces with equimolar concentration of APTES and silver nitrate in ethanol. It is discussed that amine and silane moieties in APTES contribute first to an efficient reduction on the silica and second to capping the Ag nanoparticles. The high density and homogeneity of nanoparticle nucleation is further regulated by the nanoporosity of the silica. The Ag/SiO(2) microparticles were tested for SERS using self-assembled 4-aminothiophenol monolayers, and an enhancement factor of ca. 2 × 10(6) is measured. Importantly, the SERS relative standard deviation is 36% when a single microparticle is considered and drops to 11% when sets of 10 microparticles are considered. As prepared, the microparticles are highly suitable for state-of-the-art quantitative lab-on-a-bead interrogation of specimens. American Chemical Society 2018-10-11 /pmc/articles/PMC6644844/ /pubmed/31458023 http://dx.doi.org/10.1021/acsomega.8b01247 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Rice, Daragh
Mouras, Rabah
Gleeson, Matthew
Liu, Ning
Tofail, Syed A. M.
Soulimane, Tewfik
Silien, Christophe
APTES Duality and Nanopore Seed Regulation in Homogeneous and Nanoscale-Controlled Reduction of Ag Shell on SiO(2) Microparticle for Quantifiable Single Particle SERS
title APTES Duality and Nanopore Seed Regulation in Homogeneous and Nanoscale-Controlled Reduction of Ag Shell on SiO(2) Microparticle for Quantifiable Single Particle SERS
title_full APTES Duality and Nanopore Seed Regulation in Homogeneous and Nanoscale-Controlled Reduction of Ag Shell on SiO(2) Microparticle for Quantifiable Single Particle SERS
title_fullStr APTES Duality and Nanopore Seed Regulation in Homogeneous and Nanoscale-Controlled Reduction of Ag Shell on SiO(2) Microparticle for Quantifiable Single Particle SERS
title_full_unstemmed APTES Duality and Nanopore Seed Regulation in Homogeneous and Nanoscale-Controlled Reduction of Ag Shell on SiO(2) Microparticle for Quantifiable Single Particle SERS
title_short APTES Duality and Nanopore Seed Regulation in Homogeneous and Nanoscale-Controlled Reduction of Ag Shell on SiO(2) Microparticle for Quantifiable Single Particle SERS
title_sort aptes duality and nanopore seed regulation in homogeneous and nanoscale-controlled reduction of ag shell on sio(2) microparticle for quantifiable single particle sers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644844/
https://www.ncbi.nlm.nih.gov/pubmed/31458023
http://dx.doi.org/10.1021/acsomega.8b01247
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