Activity of Co(II)–Quinalizarin: A Novel Analogue of Anthracycline-Based Anticancer Agents Targets Human DNA Topoisomerase, Whereas Quinalizarin Itself Acts via Formation of Semiquinone on Acute Lymphoblastic Leukemia MOLT-4 and HCT 116 Cells

[Image: see text] Quinalizarin (THAQ), a hydroxy-9,10-anthraquinone analogue of the family of anthracycline anticancer drugs and an inhibitor of protein kinase, was observed for its anticancer activity. Because apart from showing anticancer activity, anthracyclines and their analogues also show card...

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Detalles Bibliográficos
Autores principales: Mukherjee Chatterjee, Sayantani, Jain, Chetan Kumar, Singha, Soumen, Das, Piyal, Roychoudhury, Susanta, Majumder, Hemanta Kumar, Das, Saurabh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644896/
https://www.ncbi.nlm.nih.gov/pubmed/31459155
http://dx.doi.org/10.1021/acsomega.8b00706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644896/
https://www.ncbi.nlm.nih.gov/pubmed/31459155
http://dx.doi.org/10.1021/acsomega.8b00706

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