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Cyclopenta[d]isoxazoline β-Turn Mimics: Synthetic Approach, Turn Driving Force, Scope, and Limitations

[Image: see text] Model β-turn inducers were prepared from constrained oxazanorbornene aminols. Taking advantage of the starting materials geometry, new diastereoisomeric compounds were synthesized, introducing different amino acidic residues. The products were spectroscopically characterized (VT an...

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Detalles Bibliográficos
Autores principales: Memeo, Misal Giuseppe, Bruschi, Marco, Bergonzi, Luca, Desimoni, Giovanni, Faita, Giuseppe, Quadrelli, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645019/
https://www.ncbi.nlm.nih.gov/pubmed/31458062
http://dx.doi.org/10.1021/acsomega.8b01670