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Region-Specific Double Denaturation of Human Serum Albumin: Combined Effects of Temperature and GnHCl on Structural and Dynamical Responses

[Image: see text] In this work, we have investigated the effects of denaturing agents, guanidine hydrochloride (GnHCl) and temperature, on the overall structure, domain-I, and domain-III of human serum albumin (HSA) using circular dichroism (CD) spectroscopy and steady-state, time-resolved fluoresce...

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Detalles Bibliográficos
Autores principales:	Mohan, Vaisakh, Sengupta, Bhaswati, Acharyya, Arusha, Yadav, Rajeev, Das, Nilimesh, Sen, Pratik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645044/ https://www.ncbi.nlm.nih.gov/pubmed/31459168 http://dx.doi.org/10.1021/acsomega.8b00967

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