Cargando…

Theoretical Study on DBU-Catalyzed Insertion of Isatins into Aryl Difluoronitromethyl Ketones: A Case for Predicting Chemoselectivity Using Electrophilic Parr Function

[Image: see text] The possible mechanisms of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU)-catalyzed chemoselective insertion of N-methyl isatin into aryl difluoronitromethyl ketone to synthesize 3,3-disubstituted and 2,2-disubstituted oxindoles have been studied in this work. As revealed by calculated r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xue, Wei, Donghui, Li, Zhongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645149/ https://www.ncbi.nlm.nih.gov/pubmed/31457285 http://dx.doi.org/10.1021/acsomega.7b00907

Ejemplares similares

Zn-Catalyzed Regioselective and Chemoselective Reduction of Aldehydes, Ketones and Imines
por: Zhang, Miaomiao, et al.
Publicado: (2022)

1,3-Dipolar cycloaddition of isatin N,N′-cyclic azomethine imines with α,β-unsaturated aldehydes catalyzed by DBU in water
por: Wang, Zhan-Yong, et al.
Publicado: (2020)

Chromium(II)-catalyzed enantioselective arylation of ketones
por: Wang, Gang, et al.
Publicado: (2016)

Manganese-Catalyzed Asymmetric Hydrosilylation of Aryl Ketones
por: Ma, Xiaochen, et al.
Publicado: (2017)

Prediction of NHC-catalyzed chemoselective functionalizations of carbonyl compounds: a general mechanistic map
por: Li, Xue, et al.
Publicado: (2020)

How bulky ligands control the chemoselectivity of Pd-catalyzed N-arylation of ammonia
por: Kim, Seoung-Tae, et al.
Publicado: (2019)

Highly chemoselective ruthenium(ii)-catalyzed direct arylation of cyclic and N,N-dialkyl benzamides with aryl silanes
por: Nareddy, Pradeep, et al.
Publicado: (2017)

Chemoselective palladium-catalyzed deprotonative arylation/[1,2]-Wittig rearrangement of pyridylmethyl ethers
por: Gao, Feng, et al.
Publicado: (2016)

Enantioselective and Regiodivergent Copper-Catalyzed Electrophilic Arylation of Allylic Amides with Diaryliodonium Salts
por: Cahard, Elise, et al.
Publicado: (2015)

Computational Analysis of Enantioselective Pd-Catalyzed α-Arylation of Ketones
por: Orlandi, Manuel, et al.
Publicado: (2020)

Homogeneous and heterogeneous photoredox-catalyzed hydroxymethylation of ketones and keto esters: catalyst screening, chemoselectivity and dilution effects
por: Griesbeck, Axel G, et al.
Publicado: (2014)

Palladium catalyzed carbonylative generation of potent, pyridine-based acylating electrophiles for the functionalization of arenes to ketones
por: Liu, Yi, et al.
Publicado: (2020)

Lipase-Catalyzed Chemoselective Ester Hydrolysis of Biomimetically Coupled Aryls for the Synthesis of Unsymmetric Biphenyl Esters
por: Ehlert, Janna, et al.
Publicado: (2019)

Nickel‐Catalyzed Arylative Cyclizations of Alkyne‐ and Allene‐Tethered Electrophiles using Arylboron Reagents
por: Gillbard, Simone M., et al.
Publicado: (2022)

Palladium-catalyzed chemoselective direct α-arylation of carbonyl compounds with chloroaryl triflates at the C–Cl site
por: Chen, Zicong, et al.
Publicado: (2022)

Direct and Chemoselective Electrophilic Monofluoromethylation of Heteroatoms (O-, S-, N-, P-, Se-) with Fluoroiodomethane
por: Senatore, Raffaele, et al.
Publicado: (2020)

Catalytic Chemoselective Sulfimidation with an Electrophilic [Co(III)(TAML)](−)‐Nitrene Radical Complex
por: van Leest, Nicolaas P., et al.
Publicado: (2020)

Replacing Conventional Carbon Nucleophiles with Electrophiles: Nickel-Catalyzed Reductive Alkylation of Aryl Bromides and Chlorides
por: Everson, Daniel A., et al.
Publicado: (2012)

Highly regioselective synthesis of lactams via cascade reaction of α,β-unsaturated ketones, ketoamides, and DBU as a catalyst
por: Qin, Xin, et al.
Publicado: (2023)

Cobalt-catalyzed difluoroalkylation of tertiary aryl ketones for facile synthesis of quaternary alkyl difluorides
por: Li, Chao, et al.
Publicado: (2018)

Electronically flexible PYA ligands for efficient palladium-catalyzed α-arylation of ketones
por: Reusser, Esaïe, et al.
Publicado: (2023)

Direct Synthesis of α‐Aryl‐α‐Trifluoromethyl Alcohols via Nickel Catalyzed Cross‐Electrophile Coupling
por: Lombardi, Lorenzo, et al.
Publicado: (2022)

Facile Creation of 3-Substituted-3-Hydroxy-2-Oxindoles by Arginine-Catalyzed Aldol Reactions of α,β-Unsaturated Ketones with Isatins
por: Yan, Tingting, et al.
Publicado: (2013)

Arylation with Unsymmetrical Diaryliodonium Salts: A Chemoselectivity Study
por: Malmgren, Joel, et al.
Publicado: (2013)

An Umpolung Approach for the Chemoselective Arylation of Selenocysteine in Unprotected Peptides
por: Cohen, Daniel T., et al.
Publicado: (2015)

Highly stereoselective nickel-catalyzed difluoroalkylation of aryl ketones to tetrasubstituted monofluoroalkenes and quaternary alkyl difluorides
por: Li, Chao, et al.
Publicado: (2019)

Site‐Selective Pd‐Catalyzed C(sp(3))−H Arylation of Heteroaromatic Ketones
por: Kudashev, Anton, et al.
Publicado: (2021)

Chemoselective Decarboxylative Oxygenation of Carboxylic Acids To Access Ketones, Aldehydes, and Peroxides
por: Guan, Renpeng, et al.
Publicado: (2023)

α‐Functionalisation of Ketones Through Metal‐Free Electrophilic Activation
por: Zawodny, Wojciech, et al.
Publicado: (2020)

Ni-catalyzed cross-electrophile coupling between vinyl/aryl and alkyl sulfonates: synthesis of cycloalkenes and modification of peptides
por: Duan, Jicheng, et al.
Publicado: (2019)

Urea Derivative Catalyzed Enantioselective Hydroxyalkylation of Hydroxyindoles with Isatins
por: Wu, Hao, et al.
Publicado: (2019)

Chemoselective Covalent Modification of K-Ras(G12R) with a Small Molecule Electrophile
por: Zhang, Ziyang, et al.
Publicado: (2022)

DFT‐Guided Discovery of Ethynyl‐Triazolyl‐Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling
por: Stieger, Christian E., et al.
Publicado: (2022)

Catalyst-Dependent Chemoselectivity in the Dirhodium-Catalyzed Cyclization Reactions Between Enodiazoacetamide and Nitrosoarene: A Theoretical Study
por: Zhang, Yan, et al.
Publicado: (2019)

Hydrazinosulfonylation of aryl electrophiles: a straightforward approach for the synthesis of aryl N-aminosulfonamides
por: Hsu, Chou-Yi, et al.
Publicado: (2023)

Synthesis of aryl-thioglycopeptides through chemoselective Pd-mediated conjugation
por: Montoir, David, et al.
Publicado: (2018)

Enantioselective synthesis of α-amino ketones through palladium-catalyzed asymmetric arylation of α-keto imines
por: Wen, Wei, et al.
Publicado: (2022)

Traceless Rhodium‐Catalyzed Hydroacylation Using Alkyl Aldehydes: The Enantioselective Synthesis of β‐Aryl Ketones
por: Bouisseau, Anaïs, et al.
Publicado: (2016)

Enantioselective nickel-catalyzed arylative and alkenylative intramolecular 1,2-allylations of tethered allene–ketones
por: Di Sanza, Riccardo, et al.
Publicado: (2020)

Chemoselective reduction and oxidation of ketones in water through control of the electron transfer pathway
por: Kim, Sun Min, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_u7s02at850086nhknm39dpklob