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Khellinoflavanone, a Semisynthetic Derivative of Khellin, Overcomes Benzo[a]pyrene Toxicity in Human Normal and Cancer Cells That Express CYP1A1

[Image: see text] Cytochrome P450 family 1 (CYP1) enzymes catalyze the metabolic activation of environmental procarcinogens such as benzo[a]pyrene, B[a]P, into carcinogens, which initiates the process of carcinogenesis. Thus, stopping the metabolic activation of procarcinogens can possibly prevent t...

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Detalles Bibliográficos
Autores principales:	Sharma, Rajni, Williams, Ibidapo S., Gatchie, Linda, Sonawane, Vinay R., Chaudhuri, Bhabatosh, Bharate, Sandip B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645225/ https://www.ncbi.nlm.nih.gov/pubmed/31458985 http://dx.doi.org/10.1021/acsomega.8b01088

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