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Structural Characterization of the Amyloid Precursor Protein Transmembrane Domain and Its γ-Cleavage Site
[Image: see text] Alzheimer’s disease is the most common form of dementia that affects about 50 million of sufferers worldwide. A major role for the initiation and progression of Alzheimer’s disease has been associated with the amyloid β-peptide (Aβ), which is a protease cleavage product of the amyl...
Autores principales: | Itkin, Anna, Salnikov, Evgeniy S., Aisenbrey, Christopher, Raya, Jesus, Glattard, Elise, Raussens, Vincent, Ruysschaert, Jean-Marie, Bechinger, Burkhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645296/ https://www.ncbi.nlm.nih.gov/pubmed/31457253 http://dx.doi.org/10.1021/acsomega.7b00619 |
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