Suzuki Cross-Coupling of [2.2]Paracyclophane Trifluoroborates with Pyridyl and Pyrimidyl Building Blocks

[Image: see text] We report a new Suzuki cross-coupling protocol for high yielding derivatization of [2.2]paracyclophane with pyridyl and pyrimidyl substituents. The [2.2]paracyclophane trifluoroborate salt presented herein is a bench stable, easily accessible, and convenient substitute to former cr...

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Autores principales: Knoll, Daniel M., Bräse, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645350/
https://www.ncbi.nlm.nih.gov/pubmed/31459290
http://dx.doi.org/10.1021/acsomega.8b01774
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author Knoll, Daniel M.
Bräse, Stefan
author_facet Knoll, Daniel M.
Bräse, Stefan
author_sort Knoll, Daniel M.
collection PubMed
description [Image: see text] We report a new Suzuki cross-coupling protocol for high yielding derivatization of [2.2]paracyclophane with pyridyl and pyrimidyl substituents. The [2.2]paracyclophane trifluoroborate salt presented herein is a bench stable, easily accessible, and convenient substitute to former cross-coupling substrates. This will be of very high interest for future paracyclophane derivatization endeavors.
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spelling pubmed-66453502019-08-27 Suzuki Cross-Coupling of [2.2]Paracyclophane Trifluoroborates with Pyridyl and Pyrimidyl Building Blocks Knoll, Daniel M. Bräse, Stefan ACS Omega [Image: see text] We report a new Suzuki cross-coupling protocol for high yielding derivatization of [2.2]paracyclophane with pyridyl and pyrimidyl substituents. The [2.2]paracyclophane trifluoroborate salt presented herein is a bench stable, easily accessible, and convenient substitute to former cross-coupling substrates. This will be of very high interest for future paracyclophane derivatization endeavors. American Chemical Society 2018-09-27 /pmc/articles/PMC6645350/ /pubmed/31459290 http://dx.doi.org/10.1021/acsomega.8b01774 Text en Copyright © 2018 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Knoll, Daniel M.
Bräse, Stefan
Suzuki Cross-Coupling of [2.2]Paracyclophane Trifluoroborates with Pyridyl and Pyrimidyl Building Blocks
title Suzuki Cross-Coupling of [2.2]Paracyclophane Trifluoroborates with Pyridyl and Pyrimidyl Building Blocks
title_full Suzuki Cross-Coupling of [2.2]Paracyclophane Trifluoroborates with Pyridyl and Pyrimidyl Building Blocks
title_fullStr Suzuki Cross-Coupling of [2.2]Paracyclophane Trifluoroborates with Pyridyl and Pyrimidyl Building Blocks
title_full_unstemmed Suzuki Cross-Coupling of [2.2]Paracyclophane Trifluoroborates with Pyridyl and Pyrimidyl Building Blocks
title_short Suzuki Cross-Coupling of [2.2]Paracyclophane Trifluoroborates with Pyridyl and Pyrimidyl Building Blocks
title_sort suzuki cross-coupling of [2.2]paracyclophane trifluoroborates with pyridyl and pyrimidyl building blocks
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645350/
https://www.ncbi.nlm.nih.gov/pubmed/31459290
http://dx.doi.org/10.1021/acsomega.8b01774
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