Tandem Oxidative α-Hydroxylation/β-Acetalization Reaction of β-Ketoamides and Its Applications

[Image: see text] A tandem oxidative α-hydroxylation/β-acetalization reaction of β-ketoamides was developed in the presence of PIDA and NaOH. This reaction proceeded at 25 °C in the absence of a metal catalyst to provide 2-hydroxy-3,3-dimethoxy-N-substituted butanamides in good to excellent yields f...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiguo, Gao, Xiaolong, Yu, Haifeng, Bi, Jingjing, Zhang, Guisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645376/
https://www.ncbi.nlm.nih.gov/pubmed/31457331
http://dx.doi.org/10.1021/acsomega.7b01526

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645376/
https://www.ncbi.nlm.nih.gov/pubmed/31457331
http://dx.doi.org/10.1021/acsomega.7b01526

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