Ammonium Acetate-Promoted One-Pot Tandem Aldol Condensation/Aza-Addition Reactions: Synthesis of 2,3,6,7-Tetrahydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-ones

[Image: see text] An efficient tandem intermolecular one-pot aldol condensation/aza-addition reaction of 2-methyl-3-carbamoylpyrroles and aldehydes was developed for the synthesis of 2,3,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-ones. The reaction proceeded using only 3.0 equiv of ammonium aceta...

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Detalles Bibliográficos
Autores principales: Zhang, Zhiguo, Gao, Xiaolong, Wan, Yameng, Huang, Yuanyuan, Huang, Guoqing, Zhang, Guisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645481/
https://www.ncbi.nlm.nih.gov/pubmed/31457270
http://dx.doi.org/10.1021/acsomega.7b00626

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