Low-dose inoculation of Escherichia coli achieves robust vaginal colonization and results in ascending infection accompanied by severe uterine inflammation in mice

Escherichia coli infection of the female reproductive tract is a significant cause of disease in humans and animals, but simple animal models are lacking. Here we report that vaginal inoculation of uropathogenic E. coli strains UTI89 and CFT073 in non-pregnant, estrogen-treated mice resulted in robu...

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Detalles Bibliográficos
Autores principales: O’Brien, Valerie P., Gilbert, Nicole M., Lebratti, Tania, Agarwal, Kavita, Foster, Lynne, Shin, Haina, Lewis, Amanda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645506/
https://www.ncbi.nlm.nih.gov/pubmed/31329630
http://dx.doi.org/10.1371/journal.pone.0219941

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