Construction and in vivo/in vitro evaluation of a nanoporous ion-responsive targeted drug delivery system for recombinant human interferon α-2b delivery

BACKGROUND: Like most protein macromolecular drugs, the half-life of rhIFNɑ-2b is short, with a low drug utilization rate, and the preparation and release conditions significantly affect its stability. METHODS: A nanoporous ion-responsive targeted drug delivery system (PIRTDDS) was designed to impro...

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Detalles Bibliográficos
Autores principales: Liu, Hongfei, Zhu, Jie, Bao, Pengyue, Ding, Yueping, Shen, Yan, Webster, Thomas J, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645601/
https://www.ncbi.nlm.nih.gov/pubmed/31409991
http://dx.doi.org/10.2147/IJN.S209646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645601/
https://www.ncbi.nlm.nih.gov/pubmed/31409991
http://dx.doi.org/10.2147/IJN.S209646

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