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Preterm Birth is Associated With Increased Blood Pressure in Young Adult Women
BACKGROUND: While there is some evidence of elevated blood pressure later in life in preterm survivors, data on adult women are still lacking. Thus, we assessed the associations between preterm birth and blood pressure in young adult women. METHODS AND RESULTS: We studied 5232 young adult women who...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645636/ https://www.ncbi.nlm.nih.gov/pubmed/31164036 http://dx.doi.org/10.1161/JAHA.119.012274 |
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author | Skudder‐Hill, Loren Ahlsson, Fredrik Lundgren, Maria Cutfield, Wayne S. Derraik, José G. B. |
author_facet | Skudder‐Hill, Loren Ahlsson, Fredrik Lundgren, Maria Cutfield, Wayne S. Derraik, José G. B. |
author_sort | Skudder‐Hill, Loren |
collection | PubMed |
description | BACKGROUND: While there is some evidence of elevated blood pressure later in life in preterm survivors, data on adult women are still lacking. Thus, we assessed the associations between preterm birth and blood pressure in young adult women. METHODS AND RESULTS: We studied 5232 young adult women who volunteered for military service in Sweden between 1990 and 2007. Anthropometric and clinic blood pressure data were collected during the medical examination at the time of conscription. There was a progressive decline in systolic and diastolic blood pressures, as well as in mean arterial pressure, with increasing gestational age. Women born preterm had an adjusted increase in systolic blood pressure of 3.8 mm Hg (95% CI, 2.5–5.1; P<0.0001) and mean arterial pressure of 1.9 mm Hg (95% CI, 0.9–2.8; P=0.0001) compared with young women born at term. Rates of systolic hypertension were also considerably higher in young women born preterm (14.0% versus 8.1%, P<0.0001), as were rates of isolated systolic hypertension. The adjusted relative risk of systolic hypertension in women born preterm was 1.72 (95% CI, 1.26–2.34; P<0.001) that of women born at term or post‐term, but there was no significant difference in the risk of diastolic hypertension (adjusted relative risk, 1.60; 95% CI, 0.49–5.20). CONCLUSIONS: Young adult women born preterm display elevated systolic blood pressure and an increased risk of hypertension compared with peers born at term or post‐term. |
format | Online Article Text |
id | pubmed-6645636 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-66456362019-07-31 Preterm Birth is Associated With Increased Blood Pressure in Young Adult Women Skudder‐Hill, Loren Ahlsson, Fredrik Lundgren, Maria Cutfield, Wayne S. Derraik, José G. B. J Am Heart Assoc Original Research BACKGROUND: While there is some evidence of elevated blood pressure later in life in preterm survivors, data on adult women are still lacking. Thus, we assessed the associations between preterm birth and blood pressure in young adult women. METHODS AND RESULTS: We studied 5232 young adult women who volunteered for military service in Sweden between 1990 and 2007. Anthropometric and clinic blood pressure data were collected during the medical examination at the time of conscription. There was a progressive decline in systolic and diastolic blood pressures, as well as in mean arterial pressure, with increasing gestational age. Women born preterm had an adjusted increase in systolic blood pressure of 3.8 mm Hg (95% CI, 2.5–5.1; P<0.0001) and mean arterial pressure of 1.9 mm Hg (95% CI, 0.9–2.8; P=0.0001) compared with young women born at term. Rates of systolic hypertension were also considerably higher in young women born preterm (14.0% versus 8.1%, P<0.0001), as were rates of isolated systolic hypertension. The adjusted relative risk of systolic hypertension in women born preterm was 1.72 (95% CI, 1.26–2.34; P<0.001) that of women born at term or post‐term, but there was no significant difference in the risk of diastolic hypertension (adjusted relative risk, 1.60; 95% CI, 0.49–5.20). CONCLUSIONS: Young adult women born preterm display elevated systolic blood pressure and an increased risk of hypertension compared with peers born at term or post‐term. John Wiley and Sons Inc. 2019-06-05 /pmc/articles/PMC6645636/ /pubmed/31164036 http://dx.doi.org/10.1161/JAHA.119.012274 Text en © 2019 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Research Skudder‐Hill, Loren Ahlsson, Fredrik Lundgren, Maria Cutfield, Wayne S. Derraik, José G. B. Preterm Birth is Associated With Increased Blood Pressure in Young Adult Women |
title | Preterm Birth is Associated With Increased Blood Pressure in Young Adult Women |
title_full | Preterm Birth is Associated With Increased Blood Pressure in Young Adult Women |
title_fullStr | Preterm Birth is Associated With Increased Blood Pressure in Young Adult Women |
title_full_unstemmed | Preterm Birth is Associated With Increased Blood Pressure in Young Adult Women |
title_short | Preterm Birth is Associated With Increased Blood Pressure in Young Adult Women |
title_sort | preterm birth is associated with increased blood pressure in young adult women |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645636/ https://www.ncbi.nlm.nih.gov/pubmed/31164036 http://dx.doi.org/10.1161/JAHA.119.012274 |
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