Cargando…
Discovery of SHR9352: A Highly Potent G Protein-Biased μ-Opioid Receptor Agonist
[Image: see text] Recently, targeting the G protein-biased signaling has emerged as an attractive therapeutic strategy for treating severe acute pain with the potential to reduce the side effect of the traditional opioid drug. Herein, we describe the discovery of a highly potent G protein-biased μ-o...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6645658/ https://www.ncbi.nlm.nih.gov/pubmed/31457439 http://dx.doi.org/10.1021/acsomega.7b01452 |