Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

In cancer research, it remains challenging to functionally validate putative novel oncogenic drivers and to establish relevant preclinical models for evaluation of novel therapeutic strategies. Here, we describe an optimized and efficient pipeline for the generation of novel conditional overexpressi...

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Detalles Bibliográficos
Autores principales: Pieters, Tim, T’Sas, Sara, Demoen, Lisa, Almeida, André, Haenebalcke, Lieven, Matthijssens, Filip, Lemeire, Kelly, D’Hont, Jinke, Van Rockeghem, Frederique, Hochepied, Tino, Lintermans, Beatrice, Reunes, Lindy, Lammens, Tim, Berx, Geert, Haigh, Jody J., Goossens, Steven, Van Vlierberghe, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646380/
https://www.ncbi.nlm.nih.gov/pubmed/31332244
http://dx.doi.org/10.1038/s41598-019-46853-x

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