Involvement of G-quadruplex regions in mammalian replication origin activity

Genome-wide studies of DNA replication origins revealed that origins preferentially associate with an Origin G-rich Repeated Element (OGRE), potentially forming G-quadruplexes (G4). Here, we functionally address their requirements for DNA replication initiation in a series of independent approaches....

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Detalles Bibliográficos
Autores principales: Prorok, Paulina, Artufel, Marie, Aze, Antoine, Coulombe, Philippe, Peiffer, Isabelle, Lacroix, Laurent, Guédin, Aurore, Mergny, Jean-Louis, Damaschke, Julia, Schepers, Aloys, Ballester, Benoit, Méchali, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646384/
https://www.ncbi.nlm.nih.gov/pubmed/31332171
http://dx.doi.org/10.1038/s41467-019-11104-0

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