Upregulation of SLAMF3 on human T cells is induced by palmitic acid through the STAT5-PI3K/Akt pathway and features the chronic inflammatory profiles of type 2 diabetes

Metabolic stress-induced low-grade chronic inflammation plays an important role in the development of insulin-resistance and type 2 diabetes (T2D). Emerging evidence highlights the importance of directly elucidating T-cell activation under the obesity-induced metabolic stress condition, as T cells p...

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Detalles Bibliográficos
Autores principales: Zhou, Tong, Wang, Guixia, Lyu, Yanan, Wang, Lei, Zuo, Siyao, Zou, Jun, Sun, Lin, Zhao, Wenjie, Shu, Chang, Yang, Yong-Guang, Hu, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646391/
https://www.ncbi.nlm.nih.gov/pubmed/31332162
http://dx.doi.org/10.1038/s41419-019-1791-y

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