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Identification of novel breakpoints for locus- and region-specific translocations in 293 cells by molecular cytogenetics before and after irradiation
The human kidney embryonic 293 cell line (293 cells) is extensively used in biomedical and pharmaceutical research. These cells exhibit a number of numerical and structural chromosomal anomalies. However, the breakpoints responsible for these structural chromosomal rearrangements have not been compr...
Autores principales: | Binz, Regina L., Tian, Erming, Sadhukhan, Ratan, Zhou, Daohong, Hauer-Jensen, Martin, Pathak, Rupak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646394/ https://www.ncbi.nlm.nih.gov/pubmed/31332273 http://dx.doi.org/10.1038/s41598-019-47002-0 |
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