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Vps10-mediated targeting of Pep4 determines the activity of the vacuole in a substrate-dependent manner
The vacuole is the hydrolytic compartment of yeast cells and has a similar function as the lysosome of higher eukaryotes in detoxification and recycling of macromolecules. We analysed the contribution of single vacuolar enzymes to pexophagy and identified the phospholipase Atg15, the V-ATPase factor...
Autores principales: | Boutouja, Fahd, Stiehm, Christian M., Mastalski, Thomas, Brinkmeier, Rebecca, Reidick, Christina, El Magraoui, Fouzi, Platta, Harald W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646403/ https://www.ncbi.nlm.nih.gov/pubmed/31332264 http://dx.doi.org/10.1038/s41598-019-47184-7 |
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