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Salvage surgery combined with descending aorta resection for lung cancer
BACKGROUND: Recent retrospective studies have shown that salvage surgery can improve survival with acceptable adverse events, and this procedure has been adapted for lung cancer. However, there are no reports demonstrating the efficacy of salvage surgery combined with aortic resection. CASE PRESENTA...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646477/ https://www.ncbi.nlm.nih.gov/pubmed/31332588 http://dx.doi.org/10.1186/s40792-019-0675-9 |
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author | Kanayama, Masatoshi Ichiki, Yoshinobu Mori, Masataka Matsumiya, Hiroki Nabe, Yusuke Taira, Akihiro Shinohara, Shinji Kuwata, Taiji Takenaka, Masaru Hirai, Ayako Imanishi, Naoko Yoneda, Kazue Ikushima, Eigo Yasutsune, Toru Nishimura, Yosuke Tanaka, Fumihiro |
author_facet | Kanayama, Masatoshi Ichiki, Yoshinobu Mori, Masataka Matsumiya, Hiroki Nabe, Yusuke Taira, Akihiro Shinohara, Shinji Kuwata, Taiji Takenaka, Masaru Hirai, Ayako Imanishi, Naoko Yoneda, Kazue Ikushima, Eigo Yasutsune, Toru Nishimura, Yosuke Tanaka, Fumihiro |
author_sort | Kanayama, Masatoshi |
collection | PubMed |
description | BACKGROUND: Recent retrospective studies have shown that salvage surgery can improve survival with acceptable adverse events, and this procedure has been adapted for lung cancer. However, there are no reports demonstrating the efficacy of salvage surgery combined with aortic resection. CASE PRESENTATION: A 73-year-old man had received definitive concurrent chemoradiotherapy (carboplatin/paclitaxel, 70 Gy) for lung cancer originated from the left upper lobe and infiltrating the thoracic aorta (cT4N1M0 stage IIIA). Although the tumor has shrunk significantly (ycT4N0M0 stage IIIA), radiation pneumonitis occurred. Due to the steroid therapy, radiation pneumonitis was relieved; however, re-enlargement of the primary tumor was observed during steroid tapering. Nonetheless, the lymphatic and distant metastases were controlled. Moreover, aortic invasion was localized to the periphery of the third branch, and the tumor was considered to be resectable. Intraoperatively, we observed macroscopic evidence of aortic invasion in the periphery of the third branch; thus, left upper lobectomy combined with descending aorta resection was performed under partial extracorporeal circulation. The patient is currently active without any recurrence 21 months post-surgery. CONCLUSIONS: No clear consensus exists regarding salvage surgery combined with aortic resection for primary lung cancer. However, we believe that this surgery may improve the survival of carefully selected patients. |
format | Online Article Text |
id | pubmed-6646477 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-66464772019-08-09 Salvage surgery combined with descending aorta resection for lung cancer Kanayama, Masatoshi Ichiki, Yoshinobu Mori, Masataka Matsumiya, Hiroki Nabe, Yusuke Taira, Akihiro Shinohara, Shinji Kuwata, Taiji Takenaka, Masaru Hirai, Ayako Imanishi, Naoko Yoneda, Kazue Ikushima, Eigo Yasutsune, Toru Nishimura, Yosuke Tanaka, Fumihiro Surg Case Rep Case Report BACKGROUND: Recent retrospective studies have shown that salvage surgery can improve survival with acceptable adverse events, and this procedure has been adapted for lung cancer. However, there are no reports demonstrating the efficacy of salvage surgery combined with aortic resection. CASE PRESENTATION: A 73-year-old man had received definitive concurrent chemoradiotherapy (carboplatin/paclitaxel, 70 Gy) for lung cancer originated from the left upper lobe and infiltrating the thoracic aorta (cT4N1M0 stage IIIA). Although the tumor has shrunk significantly (ycT4N0M0 stage IIIA), radiation pneumonitis occurred. Due to the steroid therapy, radiation pneumonitis was relieved; however, re-enlargement of the primary tumor was observed during steroid tapering. Nonetheless, the lymphatic and distant metastases were controlled. Moreover, aortic invasion was localized to the periphery of the third branch, and the tumor was considered to be resectable. Intraoperatively, we observed macroscopic evidence of aortic invasion in the periphery of the third branch; thus, left upper lobectomy combined with descending aorta resection was performed under partial extracorporeal circulation. The patient is currently active without any recurrence 21 months post-surgery. CONCLUSIONS: No clear consensus exists regarding salvage surgery combined with aortic resection for primary lung cancer. However, we believe that this surgery may improve the survival of carefully selected patients. Springer Berlin Heidelberg 2019-07-22 /pmc/articles/PMC6646477/ /pubmed/31332588 http://dx.doi.org/10.1186/s40792-019-0675-9 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Case Report Kanayama, Masatoshi Ichiki, Yoshinobu Mori, Masataka Matsumiya, Hiroki Nabe, Yusuke Taira, Akihiro Shinohara, Shinji Kuwata, Taiji Takenaka, Masaru Hirai, Ayako Imanishi, Naoko Yoneda, Kazue Ikushima, Eigo Yasutsune, Toru Nishimura, Yosuke Tanaka, Fumihiro Salvage surgery combined with descending aorta resection for lung cancer |
title | Salvage surgery combined with descending aorta resection for lung cancer |
title_full | Salvage surgery combined with descending aorta resection for lung cancer |
title_fullStr | Salvage surgery combined with descending aorta resection for lung cancer |
title_full_unstemmed | Salvage surgery combined with descending aorta resection for lung cancer |
title_short | Salvage surgery combined with descending aorta resection for lung cancer |
title_sort | salvage surgery combined with descending aorta resection for lung cancer |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646477/ https://www.ncbi.nlm.nih.gov/pubmed/31332588 http://dx.doi.org/10.1186/s40792-019-0675-9 |
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