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Oxytocin Modulates the Cognitive Appraisal of the Own and Others Close Intimate Relationships

Close and intimate relationships are important promoters of health. Oxytocin and its association with social cognition have been investigated in a large number of studies, especially highlighting the neuropeptide’s involvement in attachment behavior and intimate relationships. However, mixed finding...

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Autores principales: Aguilar-Raab, Corina, Eckstein, Monika, Geracitano, Susanne, Prevost, Marie, Gold, Ian, Heinrichs, Markus, Bilderbeck, Amy, Ehlert, Ulrike, Ditzen, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646594/
https://www.ncbi.nlm.nih.gov/pubmed/31379475
http://dx.doi.org/10.3389/fnins.2019.00714
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author Aguilar-Raab, Corina
Eckstein, Monika
Geracitano, Susanne
Prevost, Marie
Gold, Ian
Heinrichs, Markus
Bilderbeck, Amy
Ehlert, Ulrike
Ditzen, Beate
author_facet Aguilar-Raab, Corina
Eckstein, Monika
Geracitano, Susanne
Prevost, Marie
Gold, Ian
Heinrichs, Markus
Bilderbeck, Amy
Ehlert, Ulrike
Ditzen, Beate
author_sort Aguilar-Raab, Corina
collection PubMed
description Close and intimate relationships are important promoters of health. Oxytocin and its association with social cognition have been investigated in a large number of studies, especially highlighting the neuropeptide’s involvement in attachment behavior and intimate relationships. However, mixed findings on exogenous oxytocin application have led to the focus on moderators and mediators, suggesting that the effects are depended on specific factors – namely context and salience. The objective of the current study was to assess the effect of intranasal oxytocin on social appraisal of own and others’ close intimate relationship characteristics. Different characteristics of relationships, including trust or closeness, between romantic couples (unknown and own) were assessed using the Couple Appraisal Task. In a randomized controlled double-blind cross-over within subject design, N = 71 healthy men and women were investigated after receiving first intranasal oxytocin and 2 weeks later placebo, or vice versa. We found an oxytocin-induced increase in the positive appraisal of one’s own overall relationship characteristics but not in the evaluation of the relationship of others. The present study – one of the first of its kind administrating oxytocin in a repeated measures cross-over design – adds further evidence to the mediating role of oxytocin in social cognition, specifically with regard to romantic relationship characteristics.
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spelling pubmed-66465942019-08-02 Oxytocin Modulates the Cognitive Appraisal of the Own and Others Close Intimate Relationships Aguilar-Raab, Corina Eckstein, Monika Geracitano, Susanne Prevost, Marie Gold, Ian Heinrichs, Markus Bilderbeck, Amy Ehlert, Ulrike Ditzen, Beate Front Neurosci Neuroscience Close and intimate relationships are important promoters of health. Oxytocin and its association with social cognition have been investigated in a large number of studies, especially highlighting the neuropeptide’s involvement in attachment behavior and intimate relationships. However, mixed findings on exogenous oxytocin application have led to the focus on moderators and mediators, suggesting that the effects are depended on specific factors – namely context and salience. The objective of the current study was to assess the effect of intranasal oxytocin on social appraisal of own and others’ close intimate relationship characteristics. Different characteristics of relationships, including trust or closeness, between romantic couples (unknown and own) were assessed using the Couple Appraisal Task. In a randomized controlled double-blind cross-over within subject design, N = 71 healthy men and women were investigated after receiving first intranasal oxytocin and 2 weeks later placebo, or vice versa. We found an oxytocin-induced increase in the positive appraisal of one’s own overall relationship characteristics but not in the evaluation of the relationship of others. The present study – one of the first of its kind administrating oxytocin in a repeated measures cross-over design – adds further evidence to the mediating role of oxytocin in social cognition, specifically with regard to romantic relationship characteristics. Frontiers Media S.A. 2019-07-16 /pmc/articles/PMC6646594/ /pubmed/31379475 http://dx.doi.org/10.3389/fnins.2019.00714 Text en Copyright © 2019 Aguilar-Raab, Eckstein, Geracitano, Prevost, Gold, Heinrichs, Bilderbeck, Ehlert and Ditzen. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Aguilar-Raab, Corina
Eckstein, Monika
Geracitano, Susanne
Prevost, Marie
Gold, Ian
Heinrichs, Markus
Bilderbeck, Amy
Ehlert, Ulrike
Ditzen, Beate
Oxytocin Modulates the Cognitive Appraisal of the Own and Others Close Intimate Relationships
title Oxytocin Modulates the Cognitive Appraisal of the Own and Others Close Intimate Relationships
title_full Oxytocin Modulates the Cognitive Appraisal of the Own and Others Close Intimate Relationships
title_fullStr Oxytocin Modulates the Cognitive Appraisal of the Own and Others Close Intimate Relationships
title_full_unstemmed Oxytocin Modulates the Cognitive Appraisal of the Own and Others Close Intimate Relationships
title_short Oxytocin Modulates the Cognitive Appraisal of the Own and Others Close Intimate Relationships
title_sort oxytocin modulates the cognitive appraisal of the own and others close intimate relationships
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646594/
https://www.ncbi.nlm.nih.gov/pubmed/31379475
http://dx.doi.org/10.3389/fnins.2019.00714
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