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Ayahuasca: Uses, Phytochemical and Biological Activities
ABSTRACT: Ayahuasca (caapi, yajé), is a psychoactive brew from the Amazon Basin region of South America traditionally considered a “master plant.” It is prepared as a decoction from Banisteriopsis caapi and Psychotria viridis, which it is thought that it stimulates creative thinking and visual creat...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646606/ https://www.ncbi.nlm.nih.gov/pubmed/31134518 http://dx.doi.org/10.1007/s13659-019-0210-5 |
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author | Estrella-Parra, Edgar Antonio Almanza-Pérez, Julio Cesar Alarcón-Aguilar, Francisco Javier |
author_facet | Estrella-Parra, Edgar Antonio Almanza-Pérez, Julio Cesar Alarcón-Aguilar, Francisco Javier |
author_sort | Estrella-Parra, Edgar Antonio |
collection | PubMed |
description | ABSTRACT: Ayahuasca (caapi, yajé), is a psychoactive brew from the Amazon Basin region of South America traditionally considered a “master plant.” It is prepared as a decoction from Banisteriopsis caapi and Psychotria viridis, which it is thought that it stimulates creative thinking and visual creativity. Native healers of the Orinoco and Amazon basins have used traditionally ayahuasca as a healing tool for multiple purposes, particularly to treat psychological disorders in the patients, with some beneficial effects experimentally and clinically validated. Recently, several syncretic religions, as the “União de Vegetal” (UDV) group in Brazil, have been spread around the world. The use of ayahuasca has been popularized by internet and smart-shops, bringing the psychoactive substance to new highs, emerging new “ayahuasqueros.” Ayahuasca has alkaloids as β-carbolines and dimethyltryptamines, which inhibit the monoamine oxidase and active the 5-HT(2A) (5-hydroxytryptamine) receptor, respectively, resulting in hallucinations in the users. Ayahuasca induces a psychedelic change in the anteroposterior coupling of the electrophysiological brain oscillations in humans. Traditional ayahuasca beverage is generating pharmacological, commercial and spiritual interest among the scientific community, government people, and different populations worldwide. The goal of this article is to report about the uses, chemistry and biological activities of ayahuasca. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-6646606 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer Singapore |
record_format | MEDLINE/PubMed |
spelling | pubmed-66466062019-07-28 Ayahuasca: Uses, Phytochemical and Biological Activities Estrella-Parra, Edgar Antonio Almanza-Pérez, Julio Cesar Alarcón-Aguilar, Francisco Javier Nat Prod Bioprospect Review ABSTRACT: Ayahuasca (caapi, yajé), is a psychoactive brew from the Amazon Basin region of South America traditionally considered a “master plant.” It is prepared as a decoction from Banisteriopsis caapi and Psychotria viridis, which it is thought that it stimulates creative thinking and visual creativity. Native healers of the Orinoco and Amazon basins have used traditionally ayahuasca as a healing tool for multiple purposes, particularly to treat psychological disorders in the patients, with some beneficial effects experimentally and clinically validated. Recently, several syncretic religions, as the “União de Vegetal” (UDV) group in Brazil, have been spread around the world. The use of ayahuasca has been popularized by internet and smart-shops, bringing the psychoactive substance to new highs, emerging new “ayahuasqueros.” Ayahuasca has alkaloids as β-carbolines and dimethyltryptamines, which inhibit the monoamine oxidase and active the 5-HT(2A) (5-hydroxytryptamine) receptor, respectively, resulting in hallucinations in the users. Ayahuasca induces a psychedelic change in the anteroposterior coupling of the electrophysiological brain oscillations in humans. Traditional ayahuasca beverage is generating pharmacological, commercial and spiritual interest among the scientific community, government people, and different populations worldwide. The goal of this article is to report about the uses, chemistry and biological activities of ayahuasca. GRAPHICAL ABSTRACT: [Image: see text] Springer Singapore 2019-05-27 /pmc/articles/PMC6646606/ /pubmed/31134518 http://dx.doi.org/10.1007/s13659-019-0210-5 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Review Estrella-Parra, Edgar Antonio Almanza-Pérez, Julio Cesar Alarcón-Aguilar, Francisco Javier Ayahuasca: Uses, Phytochemical and Biological Activities |
title | Ayahuasca: Uses, Phytochemical and Biological Activities |
title_full | Ayahuasca: Uses, Phytochemical and Biological Activities |
title_fullStr | Ayahuasca: Uses, Phytochemical and Biological Activities |
title_full_unstemmed | Ayahuasca: Uses, Phytochemical and Biological Activities |
title_short | Ayahuasca: Uses, Phytochemical and Biological Activities |
title_sort | ayahuasca: uses, phytochemical and biological activities |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646606/ https://www.ncbi.nlm.nih.gov/pubmed/31134518 http://dx.doi.org/10.1007/s13659-019-0210-5 |
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