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Concise Review: Application of Chemically Modified mRNA in Cell Fate Conversion and Tissue Engineering
Chemically modified RNA (cmRNA) has potential as a safe and efficient tool for nucleic acid‐based therapies and regenerative medicine. Modifications in the chemistry of mRNA can enhance stability, reduce immunogenicity, and thus facilitate mRNA‐based nucleic acid therapy, which eliminates risk of in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646692/ https://www.ncbi.nlm.nih.gov/pubmed/30891922 http://dx.doi.org/10.1002/sctm.18-0259 |