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Concise Review: Application of Chemically Modified mRNA in Cell Fate Conversion and Tissue Engineering

Chemically modified RNA (cmRNA) has potential as a safe and efficient tool for nucleic acid‐based therapies and regenerative medicine. Modifications in the chemistry of mRNA can enhance stability, reduce immunogenicity, and thus facilitate mRNA‐based nucleic acid therapy, which eliminates risk of in...

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Detalles Bibliográficos
Autores principales: Badieyan, Zohreh Sadat, Evans, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646692/
https://www.ncbi.nlm.nih.gov/pubmed/30891922
http://dx.doi.org/10.1002/sctm.18-0259