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Missense mutations in the C-terminal portion of the B4GALNT2-encoded glycosyltransferase underlying the Sd(a−) phenotype

Sd(a) is a high-frequency carbohydrate histo-blood group antigen, GalNAcβ1-4(NeuAcα2-3)Galβ, implicated in pathogen invasion, cancer, xenotransplantation and transfusion medicine. Complete lack of this glycan epitope results in the Sd(a−) phenotype observed in 4% of individuals who may produce anti-...

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Detalles Bibliográficos
Autores principales:	Stenfelt, Linn, Hellberg, Åsa, Möller, Mattias, Thornton, Nicole, Larson, Göran, Olsson, Martin L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646742/ https://www.ncbi.nlm.nih.gov/pubmed/31367682 http://dx.doi.org/10.1016/j.bbrep.2019.100659

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