Design and Synthesis of Imidazole and Triazole Pyrazoles as Mycobacterium Tuberculosis CYP121A1 Inhibitors

The emergence of untreatable drug‐resistant strains of Mycobacterium tuberculosis is a major public health problem worldwide, and the identification of new efficient treatments is urgently needed. Mycobacterium tuberculosis cytochrome P450 CYP121A1 is a promising drug target for the treatment of tub...

Descripción completa

Detalles Bibliográficos
Autores principales: Kishk, Safaa M., McLean, Kirsty J., Sood, Sakshi, Smith, Darren, Evans, Jack W.D., Helal, Mohamed A., Gomaa, Mohamed S., Salama, Ismail, Mostafa, Samia M., de Carvalho, Luiz Pedro S., Levy, Colin W., Munro, Andrew W., Simons, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646865/
https://www.ncbi.nlm.nih.gov/pubmed/31367508
http://dx.doi.org/10.1002/open.201900227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646865/
https://www.ncbi.nlm.nih.gov/pubmed/31367508
http://dx.doi.org/10.1002/open.201900227

Ejemplares similares